Evidence map›Paper›PMID 40624570›Full record

ReviewVeterinary research2025

Epidemiology and economics of foot-and-mouth disease: current understanding and knowledge gaps.

John M Humphreys, Carolina Stenfeldt, Donald P King, Theodore Knight-Jones, Andres M Perez, Kimberly VanderWaal, Michael W Sanderson, Antonello Di Nardo, Wudu T Jemberu, Nakarin Pamornchainavakul and 1 more

Abstract readReview
In one paragraph

Review in Veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
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  12. Phylogenetic Characterization and Seroprevalence ofAnimals : an open access journal from MDPI · 2025
    Article
  13. Review
  14. Opposing fates: a bipolar cellular model for FMDV replication shaped byFrontiers in cellular and infection microbiology · 2025
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

John M HumphreysAgricultural Research Service, National Bio and Agro-Defense Facility, U.S. Department of Agriculture, Manhattan, KS, USA.ORCID http://orcid.org/0000-0002-8464-0886
Carolina StenfeldtAgricultural Research Service, National Bio and Agro-Defense Facility, U.S. Department of Agriculture, Manhattan, KS, USA.ORCID https://orcid.org/0000-0002-2074-3886
Donald P KingThe Pirbright Institute, Woking Surrey, UK.
Theodore Knight-JonesInternational Livestock Research Institute, Addis Ababa, Ethiopia.
Andres M PerezVeterinary Population Medicine, University of Minnesota, St. Paul, MN, USA.
Kimberly VanderWaalVeterinary Population Medicine, University of Minnesota, St. Paul, MN, USA.
Michael W SandersonCenter for Outcomes Research and Epidemiology, Kansas State University, Manhattan, KS, USA.
Antonello Di NardoThe Pirbright Institute, Woking Surrey, UK.
Wudu T JemberuInternational Livestock Research Institute, Addis Ababa, Ethiopia.
Nakarin PamornchainavakulVeterinary Population Medicine, University of Minnesota, St. Paul, MN, USA.
Jonathan ArztAgricultural Research Service, National Bio and Agro-Defense Facility, U.S. Department of Agriculture, Manhattan, KS, USA. jonathan.arzt@usda.gov.ORCID https://orcid.org/0000-0002-7517-7893

Funding

Agricultural Research Service 3022-32000-064-000-DBiotechnology and Biological Sciences Research Council BBS/E/PI/230002CBiotechnology and Biological Sciences Research Council BBS/E/PI/23NB0004Biotechnology and Biological Sciences Research Council BB/X011038/1Biotechnology and Biological Sciences Research Council BB/X011046/1Department for Environment, Food and Rural Affairs, UK Government SE1131Department for Environment, Food and Rural Affairs, UK Government SE2947
6 · The paper itself

Abstract

Foot-and-mouth disease virus (FMDV) is one of the few veterinary pathogens that defines policy and global trade in animal products. Its prominence necessitates approaches to control that integrate the multiple factors contributing to the disease's biology and transmission characteristics. Central to this concept is the epidemiological FMD status (endemic or FMD-free, with or without vaccination) of a territory, which defines access to export markets. FMD epidemiology is complex, insufficiently understood, and intertwined with the biology of the virus (multiple serotypes and subtypes), global distribution (distinct regional virus pools), pathogenesis (subclinical infections and species differences), and host range (broad range of susceptible domestic and wild animals). Despite steady advances, critical knowledge gaps persist in FMD epidemiology that undermine the optimal control of FMD. This review summarizes the distinct thematic compartments of FMD epidemiology and presents the critical knowledge gaps that continue to limit the effectiveness of global, regional, and national initiatives to control and eradicate FMD.

Indexed as

Foot-and-Mouth DiseaseFoot-and-Mouth Disease VirusAnimalseconomicsepidemiologyFMDFoot-and-mouth diseaseglobal trendsmodelingmolecularpathogenesiswildlife

Identifiers

PMID40624570
PMCPMC12235859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.