Evidence map›Paper›PMID 40624543›Full record

Trial reportJournal of neuroengineering and rehabilitation2025

Electromyography (EMG)-triggered transcutaneous spinal cord and hip stimulation for gait rehabilitation in persons with chronic stroke: a randomized, controlled trial.

Mami Tani, Tomofumi Yamaguchi, Kaoru Honaga, Yoko Takahashi, Hidemi Kono, Yuhei Murakami, Reina Isayama, Koshiro Haruyama, Yuji Fujino, Tadamitsu Matsuda and 6 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of neuroengineering and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Effects of transcutaneous spinal stimulation with gait training on walking-related outcomes in stroke survivors: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Mami TaniDepartment of Rehabilitation Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Tomofumi YamaguchiDepartment of Physical Therapy, Faculty of Health Science, Juntendo University, Tokyo, Japan.
Kaoru HonagaDepartment of Rehabilitation Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Yoko TakahashiDepartment of Physical Therapy, Faculty of Health Science, Juntendo University, Tokyo, Japan.
Hidemi KonoDepartment of Rehabilitation Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Yuhei MurakamiDepartment of Rehabilitation Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Reina IsayamaDepartment of Rehabilitation Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Koshiro HaruyamaDepartment of Physical Therapy, Faculty of Health Science, Juntendo University, Tokyo, Japan.
Yuji FujinoDepartment of Physical Therapy, Faculty of Health Science, Juntendo University, Tokyo, Japan.
Tadamitsu MatsudaDepartment of Physical Therapy, Faculty of Health Science, Juntendo University, Tokyo, Japan.
Issei FukunagaDepartment of Radiological Technology, Faculty of Health Science, Juntendo University, Tokyo, Japan.
Masaaki HoriDepartment of Radiology, Toho University Omori Medical Center, Tokyo, Japan.
Akira TanumaDepartment of Rehabilitation Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Futoshi WadaDepartment of Rehabilitation Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kozo HatoriDepartment of Rehabilitation Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Toshiyuki FujiwaraDepartment of Rehabilitation Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan. t-fujiwara@juntendo.ac.jp.

Funding

JSPS KAKENHI 26350587
6 · The paper itself

Abstract

backgroundTranscutaneous spinal stimulation has been applied to gait rehabilitation for persons with neurological diseases. The authors developed electromyography-triggered transcutaneous spinal cord and hip stimulation for gait rehabilitation and called this system FAST walk. This study aimed to assess the effect of FAST walk in a randomized, controlled trial.

methodsAll participants were randomly allocated to three groups: FAST walk combined with treadmill gait training (FAST walk); spinal stimulation combined with treadmill gait training (spinal stim); and treadmill gait training (treadmill). Participants performed two sets of 15-min treadmill gait training with 5-min intervals in the FAST walk, spinal stim, and treadmill groups. Gait training was performed twice weekly for a total of 10 sessions. The primary outcome was 10-m walking time. The secondary outcomes were the time symmetry index (TSI) with gait analysis and spinal reciprocal inhibition on the conditioned-test H reflex study.

resultsTwenty persons with chronic stroke participated in this study, and 17 persons completed this study. For the primary outcome, there was no significant interaction between time and intervention in 10-m walking time on two-way analysis of covariance (ANCOVA) (P = 0.382, η

conclusionsThe newly developed electromyography-triggered transcutaneous spinal cord and hip stimulation, FAST walk, is safe and may improve the gait speed of persons with chronic stroke. We did not, however, find a significant between-group difference among the FAST walk, spinal stim, and treadmill gait groups.

trial registrationJapan Registry of Clinical Trial (JRCT registration ID: jRCTs032180289).

Indexed as

ElectromyographyExercise TherapyGait Disorders, NeurologicSpinal Cord StimulationStroke RehabilitationTranscutaneous Electric Nerve StimulationAdultAgedChronic DiseaseFemaleGaitHipHumansMaleMiddle AgedStrokeCerebrovascular diseaseElectrical stimulationHemiparesisLocomotionMotor functionNeuromodulationNeurorehabilitationSpinal reflexTranscutaneous spinal cord stimulation

Identifiers

PMID40624543
PMCPMC12232820

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.