Evidence map›Paper›PMID 40624531›Full record

ArticleEuropean journal of medical research2025

Predictive role of serum sST2 for heart failure in children with severe pneumonia.

Qingsong Wu, Xinxin Zheng, Xinfan Lin, Linfeng Xie, Liangwan Chen, Zhihuang Qiu

Abstract read
In one paragraph

Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qingsong Wu *Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Xinquan Road 29, Fuzhou, 350001, Fujian, People's Republic of China. wqs9005@163.com.
Xinxin Zheng *Fuzhou Children's Hospital of Fujian Province, Fuzhou, Fujian, People's Republic of China.
Xinfan LinDepartment of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Xinquan Road 29, Fuzhou, 350001, Fujian, People's Republic of China.
Linfeng XieDepartment of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Xinquan Road 29, Fuzhou, 350001, Fujian, People's Republic of China.
Liangwan ChenDepartment of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Xinquan Road 29, Fuzhou, 350001, Fujian, People's Republic of China.
Zhihuang QiuDepartment of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Xinquan Road 29, Fuzhou, 350001, Fujian, People's Republic of China. qzhflm@126.com.

Funding

Fujian Provincial Center for Cardiovascular Medicine Construction Project No.2021-76Fujian Provincial Natural Science Foundation of China 2024J01627Fujian Provincial Special Reserve Talents Laboratory No.2021-25Fuzhou level science and technology plan project 2020-WS-61
6 · The paper itself

Abstract

objectiveTo evaluate the predictive value of soluble suppression of tumorigenesis-2 (sST2) for heart failure (HF) in children hospitalized with severe pneumonia.

methodsA total of 109 children with severe pneumonia who were admitted to our hospital between January 2022 and December 2023 were selected. They were divided into HF and non-HF groups based on whether they developed HF. Clinical characteristics and clinical outcome data of the two groups were analyzed using relative factors analysis and logistic regression analysis.

resultsThe HF and non-HF groups consisted of 35 and 74 patients, respectively. Significant differences were observed between the groups in terms of age [20.0 (11.0-38.0) vs. 60.0 (36.0-96.0) months, P < 0.001], body mass index (16.7 ± 2.0 vs. 18.3 ± 2.5 kg/m

conclusionElevated sST2 shows potential as an independent risk factor for HF in children with severe pneumonia, but further studies are needed before routine clinical adoption.

Indexed as

Heart FailureInterleukin-1 Receptor-Like 1 ProteinPneumoniaBiomarkersChildChild, PreschoolFemaleHumansInfantMalePrognosisRetrospective StudiesRisk FactorsSeverity of Illness IndexBiomarkersIL1RL1 protein, humanInterleukin-1 Receptor-Like 1 ProteinHeart failurePediatric severe pneumoniaPredictive valueSoluble suppression of tumorigenesis-2 (sST2)

Identifiers

PMID40624531
PMCPMC12236013

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.