Observational studyBMC nephrology2025
Evaluation of intradialytic hypoxemia development in intensive care patients.
Observational study in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Short-Term Effects of Intradialytic Hypoxemia on Plasma Markers of Hypoxia.International journal of molecular sciences · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHypoxemia is a significant factor contributing to increased mortality in intensive care patients and remains a prevalent issue. Although numerous conditions are well documented to lead to hypoxemia, intradialytic hypoxemia (IDH) occurring during dialysis is often overlooked. IDH is characterized by a decrease in arterial oxygen saturation below 90% or partial oxygen pressure (PaO₂) below 80 mmHg, and it may compromise tissue perfusion, adversely affecting patient prognosis. This study aims to enhance awareness of IDH in critically ill patients and to propose proactive strategies for the prevention of associated complications.
methodThe single-center observational study included 93 intensive care patients. Patients' arterial and central venous blood gas values were measured before dialysis (baseline), at the third hour of dialysis (3rd hour), and one-hour post-dialysis (5th hour). The study evaluated PaO₂, partial pressure of carbon dioxide (PaCO₂), central venous oxygen saturation (ScvO₂), mean arterial pressure (MAP), perfusion index (PI) and the temperature gradient between the forearm and fingertip. Statistical analyses were conducted using the SPSS 26 software.
findingsIn patients who did not survive, a significant decrease was observed in PaO₂, ScvO₂, and perfusion index (PI) values at the third hour, while PaCO₂ levels and the central venous-to-arterial temperature gradient increased. No significant change was detected in mean arterial pressure (MAP) values. A partial trend toward improvement in these parameters was observed following dialysis. Survival rates among these patients were low, and survival duration was found to be short. DISCUSSION AND
conclusionThese changes indicate a deterioration in oxygen delivery and tissue perfusion. Therefore, close monitoring of these parameters during dialysis is of critical importance for the early identification of intradialytic hypotension (IDH) and the prevention of potential complications. Moreover, the observed low survival rates and short survival duration suggest that intradialytic pathophysiological changes may have a markedly adverse impact on patient prognosis. CLINICAL TRIAL NUMBER: Not applicable.
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