Evidence map›Paper›PMID 40624418›Full record

Trial reportSurgical endoscopy2025

Lymphatic and vascular anatomy define surgical principles for radical treatment of distal duodenal and proximal jejunal tumors.

Teodor Vasic, Milena Stimec, Bojan Vladimir Stimec, Bjørn Edwin, Dejan Ignjatovic

Erratum issued Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05670574 (Surgery With Extended), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05670574 naunknown statusnot on this map

Surgery With Extended (D3) Mesenterectomy for Small Bowel Tumors

TypeinterventionalSponsorSykehuset i Vestfold HFRan2016 to 2025Enrolled150ConditionsSmall Bowel Cancer, Small Bowel Carcinoid Tumor, Quality of Life, Lymph Node MetastasesArmsSurgery with extended (D3) mesenterectomy for small bowel tumors
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Teodor VasicClinic for Digestive Surgery, Faculty of Medicine, University Clinical Centre of Serbia, University of Belgrade, Belgrade, Serbia.ORCID http://orcid.org/0000-0002-4862-7561
Milena StimecAnatomy Unit, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Bojan Vladimir StimecAnatomy Unit, Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-4488-9812
Bjørn EdwinIntervention Centre, Oslo University Hospital, Oslo, Norway.ORCID http://orcid.org/0000-0002-3137-6225
Dejan IgnjatovicDepartment of Digestive Surgery, Akershus University Hospital, Oslo, Norway. dejan.ignjatovic@medisin.uio.no.ORCID http://orcid.org/0000-0002-8565-0568

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe arterial ligation level and the lymphadenectomy extent for surgical treatment of distal duodenal/proximal jejunal tumors are not standardized.

aimTo define morphometric and topographic specifics of the superior jejunal artery (SJA) and the superior jejunal vein (SJV), and the width of arterial lymphovascular bundles through lymphatic clearances. By extrapolating results from two methodologies, the goal is to determine the arterial ligation level and the lymphadenectomy extent for duodenojejunal tumor treatment. MATERIAL AND

methodsThe first series included an analysis of preoperative 3D-CT vascular reconstructions from 97 patients. The second series included 11 dissected cadavers where the course of the proximal mesenteric lymphatics was followed. The SJA was defined as the uppermost jejunal artery (JA) counted from the ileocolic artery (ICA) origin.

resultsSJA proper was present in 72 cases (74.2%). The mean SJA caliber was 3.4 ± 1.2 mm. SJA originated 17.5 ± 16.8 mm cranial to the middle colic artery (MCA) origin and was found cranial to it in 84 cases. SJA originated caudal to the inferior pancreatic border in 80 cases (82.8%) and cranial in 17 (17.2%). SJV coursed anteriorly to the superior mesenteric artery in 29 cases (29.9%). The distances of the cranial and caudal lymphatics following SJA at the level of the arterial origin were 1.15 ± 0.53 mm and 0.6 ± 0.35 mm.

conclusionsTo achieve adequate lymphatic clearance, it is crucial to ligate the tumor-feeding SJA at its origin. The conical arrangement of the SJA lymphatics underscores the necessity of a mesenterectomy extending both cranially and caudally, including lymphadenectomy along the adjacent JA to the level of the first arcade.

trial registration"Surgery with Extended (D3) Mesenterectomy for Small Bowel Tumors" registered at https://classic. CLINICALTRIALS: gov/ct2/show/NCT05670574 NCT05670574.

Indexed as

Duodenal NeoplasmsJejunal NeoplasmsJejunumLymphatic VesselsLymph Node ExcisionAdultAgedAged, 80 and overCadaverFemaleHumansImaging, Three-DimensionalLigationMaleMesenteric Artery, SuperiorMiddle AgedD3 volumeDuodenumJejunal arteryJejunumLymphadenectomySurgical technique

Identifiers

PMID40624418
PMCPMC12287156

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.