Evidence map›Paper›PMID 40624231›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

Prediction model of recurrence in patients with lumbar disc herniation after unilateral biportal endoscopy spinal surgery- XGBoost machine learning model can be interpreted based on SHAP.

Yi Rong, Hao Yu, Zhen Hua, Jian-Feng Chen, Jian-Wei Wang

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yi Rong *Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China.
Hao Yu *Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China. yuhao495422190@qq.com.
Zhen HuaWuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China.
Jian-Feng ChenWuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China.
Jian-Wei WangWuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China. wxzy006@njucm.edu.cn.

Funding

National Natural Science Foundation of China 82274546the National Natural Science Foundation of China NO. 82205142the Postgraduate Research & Practice Innovation Program of Jiangsu Province KYCX22_2062
6 · The paper itself

Abstract

backgroundPatients with single-segment lumbar disc herniation(LDH) who have undergone unilateral biportal endoscopic (UBE) spinal surgery face the risk of postoperative recurrence. The potential factors for recurrence of lumbar disc herniation(rLDH) are not fully understood.

aimsThis study aimed to investigate the risk factors for rLDH after UBE spinal surgery and establish a risk factor prediction model using machine learning to predict the recurrence rate. STUDY

designThis study used LASSO regression for feature screening, XGBoost for machine learning model construction, ROC curve analysis, calibration curve analysis, clinical decision curve analysis, specificity, sensitivity, accuracy, and F1 score to evaluate the model’s performance.

resultsThe clinical data of 271 patients with LDH were retrospectively analyzed. All patients have undergone UBE spinal surgery. 47 patients relapsed, with a recurrence rate of 17.3%. The XGBoost model predicted a higher AUC for rLDH (training: 0.927, 95%CI: 0.882–0.958; Test: 0.866, 95%CI: 0.760–0.937). The importance of SHAP variables in the model in descending order is: “Width of Protrusion Base(WPB), “” Bone Removal Range(BRR), “"Modic Change,” " Type of LDH,” “Middle Vertebral space Height(MVH),” “Hyperlipidemia.”

conclusionThe large WPB、high WPB、 extensive BRR, and preoperative Modic Changes are more likely to develop rLDH. Hyperlipidemia and prolapsed disc herniation are negatively correlated with rLDH. RELEVANCE TO CLINICAL PRACTICE: Improve the ability to predict the rLDH after UBE spinal surgery. This will enable clinicians to intervene early and improve postoperative outcomes.

Indexed as

EndoscopyIntervertebral Disc DisplacementLumbar VertebraeMachine LearningAdultBoosting Machine Learning AlgorithmsFemaleHumansMaleMiddle AgedPrediction AlgorithmsPredictive Learning ModelsRecurrenceRetrospective StudiesRisk FactorsLumbar disc herniationMachine learningRecurrenceSHAPUnilateral biportal endoscopic spinal surgery

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.