Evidence map›Paper›PMID 40624230›Full record

ArticleScientific reports2025

Comparison of different tracheal intubation methods for unstable upper cervical spine injuries in a human cadaver model.

Davut Deniz Uzun, Niko R E Schneider, Shiyao Liao, Felix C F Schmitt, Markus A Weigand, Michael Kreinest, Erik Popp, Frank Weilbacher

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Davut Deniz UzunMedical Faculty Heidelberg, Department of Anesthesiology, Heidelberg University, Heidelberg, Germany. deniz.uzun@med.uni-heidelberg.de.ORCID http://orcid.org/0000-0002-0559-8684
Niko R E SchneiderMedical Faculty Heidelberg, Department of Anesthesiology, Heidelberg University, Heidelberg, Germany.
Shiyao LiaoDepartment of Orthopedic Surgery, Zhejiang Provincial People's Hospital and People's Hospital of Hangzhou Medical College, Hangzhou, China.
Felix C F SchmittMedical Faculty Heidelberg, Department of Anesthesiology, Heidelberg University, Heidelberg, Germany.
Markus A WeigandMedical Faculty Heidelberg, Department of Anesthesiology, Heidelberg University, Heidelberg, Germany.
Michael KreinestBG Trauma Center Ludwigshafen, Ludwigshafen, Germany.
Erik PoppMedical Faculty Heidelberg, Department of Anesthesiology, Heidelberg University, Heidelberg, Germany.
Frank WeilbacherMedical Faculty Heidelberg, Department of Anesthesiology, Heidelberg University, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In severe trauma, it is estimated that approximately 2% of patients will sustain a spinal cord injury. The optimal method for advanced airway management that will minimize any associated cervical spine movement remains a topic of debate. Therefore, the aim of this study is to compare the effects of different tracheal intubation techniques in unstable injuries of the cervical spine. Tracheal intubation using conventional laryngoscopy (CL), video laryngoscopy (VL) or flexible bronchoscopic intubation (FO) was performed in six fresh human cadavers. Compression of the dural sac as well as angulation, distraction and intubation time were assessed by myelography in the presence of isolated atlanto-occipital dislocation (AOD) and of combined atlanto-occipital dislocation with atlanto-axial instability (AAI). In case of an isolated AOD, FO intubation resulted in significantly less compression of the dural sac at both levels compared to CL (- 0.46 mm vs. - 1.31 mm; p < 0.001, r = .66) for C0/C1 and (- 0.09 mm vs. - 0.19 mm; p =  < 0.05, r = .36) for C1/C2 and VL (- 0.46 mm vs. - 0.64 mm; p =  < 0.05, r = .42 for C0/C1 and (- 0.09 mm vs. - 0.22 mm; p =  < 0.01, r = .52) for C1/C2. Atlanto-axial Angulation in simultaneous AOD and AAI, the differences between CL and VL were significantly in favor of VL (4.1° vs. 3.2°; p =  < 0.05, r = .39), and using FO resulted in less angulation than CL (2.5° vs. 4.1°; p =  < 0.001, r = .60) and VL (2.5° vs. 3.2°; p =  < 0.05). FO required longer in the case of combined AOD and AAI (FO 16.6 s vs. CL 9.8 s; p =  < 0.001, r = .56), (FO 16.6 s vs. VL 9.7 s; p =  < 0.001, r = .56). The study demonstrated that tracheal intubation using VL caused significant less compression of the dural sac than the CL. FO showed the lowest compression at all measuring points, but took almost twice as long. For elective or stable patients, where time to airway management is not a relevant factor, FO appears to be the safest method. However, FO is not available everywhere, and in urgent emergency situations, the longer duration may not be acceptable. In such cases, video laryngoscopy can represent a compromise between duration and patient safety, and most physicians have more clinical experience with VL than with FO.

Indexed as

Cervical VertebraeIntubation, IntratrachealSpinal InjuriesAgedCadaverFemaleHumansLaryngoscopyMaleMiddle AgedCervical spineDirect laryngoscopyFlexible bronchoscopic intubationTracheal intubationVideo laryngoscopy

Identifiers

PMID40624230
PMCPMC12234655

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.