Evidence map›Paper›PMID 40624126›Full record

ArticleScientific reports2025

Highly selective solid phase extraction of clonazepam from water using a urea modified MOF prior to HPLC analysis.

Marzieh Sharifi-Rad, Asma Khoobi, Mostafa Khajeh, Massoud Kaykhaii, Ali Reza Oveisi

Abstract read
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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marzieh Sharifi-RadDepartment of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan, 98135-674, Iran.ORCID http://orcid.org/0000-0002-8206-4168
Asma KhoobiDepartment of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan, 98135-674, Iran. a.khoobi@science.usb.ac.ir.ORCID http://orcid.org/0000-0002-1298-6036
Mostafa KhajehDepartment of Chemistry, University of Zabol, Zabol, Iran.ORCID http://orcid.org/0000-0002-7097-2898
Massoud KaykhaiiDepartment of Analytical Chemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská dolina, Ilkovičova 6, Bratislava, 842 15, Slovak Republic.ORCID http://orcid.org/0000-0003-2890-9286
Ali Reza OveisiDepartment of Organic Chemistry, Faculty of Chemistry, Lorestan University, Khorramabad, 68151-44316, Iran.ORCID http://orcid.org/0000-0002-0075-211X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of pharmaceutical pollutants, such as clonazepam (CZP), in aquatic environments poses significant risks to ecosystems and human health. This study introduces a novel solid-phase extraction (SPE) method utilizing a urea-modified metal-organic framework (MIL-101(Fe)-Urea) for the selective preconcentration and quantification of CZP in environmental water samples, then analyzed by high performance liquid chromatography analysis. The MIL-101(Fe)-Urea adsorbent was synthesized through a post-synthetic modification approach and characterized using FTIR, PXRD, SEM, BET, and EDX techniques. Key extraction parameters, including pH, adsorbent dosage, extraction/desorption times, and sample volume, were optimized to achieve maximum adsorption efficiency. Under optimal conditions, the method demonstrated excellent linearity (R

Indexed as

ClonazepamMetal-Organic FrameworksSolid Phase ExtractionUreaWater Pollutants, ChemicalAdsorptionChromatography, High Pressure LiquidEnvironmental MonitoringLimit of DetectionClonazepamMetal-Organic FrameworksMIL-101UreaWater Pollutants, ChemicalBenzodiazepinesDrugEnvironmental monitoringMetal-organic frameworkPost-synthetic modificationSolid-phase extraction

Identifiers

PMID40624126
PMCPMC12234890

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.