Evidence map›Paper›PMID 40624077›Full record

ArticleScientific reports2025

Predictive factors at initial visit for sunset glow fundus in Vogt-Koyanagi-Harada disease.

Tetsuya Muto, Masaaki Sakamoto, Shigeki Machida, Shinichiro Imaizumi, Tetsuju Sekiryu

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Vogt-Koyanagi-Harada disease recurrence after laser treatment: A case report.The Journal of international medical research · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tetsuya MutoDepartment of Ophthalmology, Dokkyo Medical University Saitama Medical Center, Koshigaya, 343-8555, Japan. ueda.castle@gmail.com.
Masaaki SakamotoDepartment of Ophthalmology, Dokkyo Medical University Saitama Medical Center, Koshigaya, 343-8555, Japan.
Shigeki MachidaDepartment of Ophthalmology, Dokkyo Medical University Saitama Medical Center, Koshigaya, 343-8555, Japan.
Shinichiro ImaizumiDepartment of Ophthalmology, Imaizumi Eye Hospital, 20-9 Domaecho, Koriyama, 963-8877, Japan.
Tetsuju SekiryuDepartment of Ophthalmology, Fukushima Medical University, Fukushima, 960-1295, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to identify factors present at the initial visit for the development of sunset glow fundus (SGF) in Vogt-Koyanagi-Harada (VKH) disease. A total of 139 eyes from 70 naïve patients with acute VKH disease who underwent pulse steroid therapy were categorized into "SGF" and "non-SGF" groups based on fundus appearance at 12 months post-therapy. Multivariable analysis revealed that patients with meningismus (p = 0.004), incomplete type (p = 0.035), and probable type (p = 0.002) in older revised diagnostic criteria; ex-smoker (p = 0.016), and smoker (p = 0.010) status; high logarithmic best-corrected visual acuity (BCVA) (p < 0.001); high spherical equivalent (SE) (p = 0.005); shallow peripheral anterior chamber depth (ACD) (p < 0.001); narrow anterior chamber angle (ACA) (p = 0.015); increased pupil diameter (p < 0.001); and thicker cornea (p = 0.019) were associated with SGF. The optimal cut-off values for predicting SGF were identified as follows: logarithmic BCVA greater than 0.261, SE exceeding - 2.813 D, peripheral ACD less than 2.138 mm, ACA less than 40.55 °, pupil diameter exceeding 3.040 mm, and corneal thickness exceeding 579.500 μm. Patients with VKH disease who exhibit above risk factors require early and careful management.

Indexed as

Uveomeningoencephalitic SyndromeAdultFemaleFundus OculiHumansMaleMiddle AgedRetrospective StudiesRisk FactorsVisual AcuityYoung AdultCorneal thicknessPupil diameterSunset glow fundusVisual acuityVogt–Koyanagi–Harada disease

Identifiers

PMID40624077
PMCPMC12234651

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.