ArticleNature communications2025
The haplotype-resolved telomere-to-telomere genome and OMICS analyses reveal genetic responses to tapping in rubber tree.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Haplotype-resolved regulation of secondary metabolism in cannabis.Horticulture research · 2026Article
- Haplotype-resolved T2T genome and population resequencing provide insights into the domestication and mogroside biosynthesis ofHorticulture research · 2026Article
- Genome-wide identification and cold stress expression of inducer of CBF expression (ICE) transcription factors in Taraxacum kok-saghyz.Functional & integrative genomics · 2026Article
- Article
- Article
- Type-B authentic response regulators regulate natural rubber biosynthesis by targeting small rubber particle proteins in rubber-producing plants.Functional & integrative genomics · 2026Article
- Genome-Wide Identification and Expression Analysis of the WOX Family Reveals Potential Roles in Stem Development ofPlants (Basel, Switzerland) · 2026Article
- Genome-wide identification and expression profile ofFrontiers in plant science · 2026Article
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19 authors.
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Abstract
Rubber tree (Hevea brasiliensis) is the primary source of natural rubber and economically important. We present the haplotype-resolved, telomere-to-telomere, gap-free genome assembly of the cultivar CATAS 7-33-97, with both haplotypes containing complete telomeric and centromeric regions. Structural variations, including a 32.71 Mb inversion on chromosome 8, are identified. The fully assembled 36 chromosomes enable comprehensive identification of rubber biosynthesis genes and their allele-specific expression. By integrating transcriptomic and metabolomic data, we reconstruct the rubber biosynthesis pathway and confirm the mevalonate (MVA) pathway as the major carbon source for rapid latex regeneration during tapping. Jasmonic acid (JA) plays a key role in promoting rubber yield by enhancing biosynthetic activity in response to mechanical wounding. We propose a model where JA-induced myelocytomatosis proteins 2 activate mevalonate kinase 1 expression, boosting MVA synthesis and rubber production. These findings provide insights into rubber tree genomics and its molecular response to tapping.
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