Evidence map›Paper›PMID 40623891›Full record

ArticleBMJ open2025

Use of an electronic medication management application to support Pharmacists Review to Optimise Medicines in Residential Aged Care (PROMPT-RC): a study protocol for a parallel cluster randomised controlled trial.

Amy Theresa Page, Dee Mangin, Hend Almutairi, Esa Y H Chen, Kenneth Lee, Nagham Ailabouni, Jacinta Johnson, Kathleen Potter, Nahal Mavaddat, Rhonda Marise Clifford and 8 more

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Amy Theresa PageCentre for Optimisation of Medicines, The University of Western Australia, Perth, Western Australia, Australia amy.page@uwa.edu.au.ORCID http://orcid.org/0000-0002-2084-8469
Dee ManginPublic Health and General Practice, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand.
Hend AlmutairiPharmacy, School of Allied Health, The University of Western Australia, Perth, Western Australia, Australia.ORCID http://orcid.org/0000-0003-1326-6943
Esa Y H ChenCentre for Medicine Use and Safety, Monash University, Parkville, Victoria, Australia.
Kenneth LeePharmacy, School of Allied Health, The University of Western Australia, Crawley, Western Australia, Australia.ORCID http://orcid.org/0000-0003-3022-4868
Nagham AilabouniThe University of Queensland, Brisbane, Queensland, Australia.
Jacinta JohnsonUniversity of South Australia, Adelaide, South Australia, Australia.
Kathleen PotterRyman Healthcare, Christchurch, New Zealand.ORCID http://orcid.org/0000-0001-7806-8708
Nahal MavaddatSchool of Medicine, The University of Western Australia, Perth, Western Australia, Australia.
Rhonda Marise CliffordPharmacy, School of Medicine and Pharmacology, The University of Western Australia, Perth, Western Australia, Australia.
Elton LoboThe University of Queensland, Brisbane, Queensland, Australia.
Loretta BaldassarEdith Cowan University, Joondalup, Western Australia, Australia.
Liza SeubertSchool of Medicine and Pharmacology, The University of Western Australia, Crawley, Western Australia, Australia.
Dennis PetrieCentre for Health Economics, Monash University, Melbourne, Victoria, Australia.
Kate WangRMIT University, Melbourne, Victoria, Australia.
Sarah HoskingDeakin University, Burwood, Victoria, Australia.
Jenny TaskerWA Centre for Health and Ageing, Perth, Western Australia, Australia.
Christopher Etherton-BeerMedical School, The University of Western Australia, Crawley, Western Australia, Australia.ORCID http://orcid.org/0000-0001-5148-0188

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMost older adults living in residential aged care facilities (RACFs) have at least one marker of potentially suboptimal prescribing. Pharmacists play a crucial role in medication management, with their effectiveness enhanced by using computerised decision support tools. The Pharmacists Review to Optimise Medicines in Residential Aged Care (PROMPT-RC) study aims to optimise medicine use by providing pharmacists in RACFs with an electronic medicine management app with integrated decision support (AusTAPER App/Pathway) to use as part of medication reviews they undertake. METHODS AND ANALYSIS: The PROMPT-RC study is a parallel cluster randomised controlled trial design involving Australian RACFs. It will assess if pharmacists' use of the AusTAPER App/Pathway for medication reviews improves medication regimens for RACF residents compared with usual care. Pharmacists in RACFs randomised to the intervention arm will be trained to use the AusTAPER App/Pathway, which flags potentially inappropriate medicines (PIMs) across a person's entire medicine regimen. Pharmacists in RACFs randomised to the control arm will not have access to the AusTAPER App/Pathway-they will continue to provide usual care. The primary outcome is the difference in the number of regular medicines between treatment arms at 12 months. Secondary outcomes will measure the number of regular and pro re nata medicines, PIMs, medicine administration times, medicine regimen complexity, use of antipsychotics, antidepressants, and benzodiazepines, quality of life, mortality, instances of physical restraint, and the number of falls, hospitalisations and general practitioner/health professional visits. The cost-effectiveness of the AusTAPER App/Pathway compared with usual care will be calculated. Data collection will occur at baseline, 3, 6, 9 and 12 months postrandomisation and 3 and 6 months prebaseline. We aim to recruit 668 participants to adjust for an estimated 10% loss to follow-up, giving 334 participants in each arm. Data analysis will follow an intention-to-treat approach using a linear mixed model. ETHICS AND DISSEMINATION: Ethical approval was obtained from The University of Western Australia Human Research Ethics Committee (Reference: 2024/ET000525; approved 14 August 2024). Reciprocal approval was also obtained in other states. This study is registered on the Australian New Zealand Clinical Trials Registry (https://anzctr.org.au). Trial findings will be disseminated through national and international peer-reviewed publications and conferences. TRIAL REGISTRATION NUMBER: ACTRN12624001409561.

Indexed as

Homes for the AgedInappropriate PrescribingMedication Therapy ManagementPharmacistsAgedAustraliaHumansMobile ApplicationsRandomized Controlled Trials as TopicMedication ReviewMedicineNursing HomesPharmacists

Identifiers

PMID40623891
PMCPMC12258304

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.