ArticleBMJ case reports2025
Idiopathic pulmonary haemosiderosis in childhood.
Article in BMJ case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This report describes a case involving a boy in his middle childhood with a history of recurrent iron deficiency anaemia, accompanied by respiratory distress, tachypnoea and cyanosis. The respiratory distress improved with pulse doses of methylprednisolone and respiratory support using high-flow oxygen via heated humidified nasal cannula. During each admission, respiratory distress was resolved after administering pulse methylprednisolone. The child was admitted five times with such episodes in the paediatric intensive care unit (PICU). X-rays and high-resolution CT of the chest performed during respiratory distress showed diffuse ground-glass opacities and multiple areas of consolidation. After excluding sepsis, autoimmune diseases and vasculitis, a bronchoscopic alveolar lavage was conducted, revealing haemosiderin-laden macrophages. Having ruled out other causes of diffuse alveolar haemorrhage, this case was identified as idiopathic pulmonary haemosiderosis (IPH). Following discharge from the PICU and resolution of respiratory distress, the child was started on maintenance immunosuppression with prednisolone at 15 mg/day.
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