Evidence map›Paper›PMID 40623755›Full record

SynthesisBMJ open2025

Association between left atrial appendage volume and atrial fibrillation recurrence after catheter ablation: a systematic review and meta-analysis.

Pengfei Chen, Ming Guo, Chen Chen, Deng Pan, Jianpeng Du, Dazhuo Shi

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pengfei ChenChina Academy of Chinese Medical Sciences Xiyuan Hospital, Beijing, China.ORCID http://orcid.org/0000-0001-5161-5089
Ming GuoChina Academy of Chinese Medical Sciences Xiyuan Hospital, Beijing, China.
Chen ChenChina Academy of Chinese Medical Sciences Xiyuan Hospital, Beijing, China.
Deng PanHangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, China.ORCID http://orcid.org/0000-0002-3343-0088
Jianpeng DuChina Academy of Chinese Medical Sciences Xiyuan Hospital, Beijing, China 13811518062@163.com.
Dazhuo ShiXiyuan Hospital of CACMS, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the association between left atrial appendage volume (LAAV) and atrial fibrillation (AF) recurrence after catheter ablation (CA) and explore the potential mechanism.

designSystematic review and meta-analysis. DATA SOURCES: PubMed, EMBASE, Web of Science and Cochrane Library databases were searched systematically from inception through 28 September 2024 to identify relevant studies. ELIGIBILITY CRITERIA: Observational studies that estimated the association between LAAV and AF recurrence. DATA EXTRACTION AND SYNTHESIS: Two independent investigators screened studies for inclusion and extracted data. Statistical heterogeneity was assessed using the Cochrane Q-test and I², with p<0.1 or I² > 50% indicating significant heterogeneity. This study used a random-effects model to account for potential heterogeneity. The quality of the included studies was assessed using the Newcastle-Ottawa Scale (NOS), Risk of Bias in Non-randomized Studies of Interventions (ROBINS-I tool) and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Publication bias was examined through funnel plots and Egger's test.

resultSeventeen studies (3078 patients) were included. Meta-analysis of 11 studies suggested that LAAV was significantly associated with the risk of AF recurrence in both univariate (HR 1.06, 95%CI 1.04 to 1.08, p<0.01; I

conclusionsOur study suggests that LAAV may be a significant predictor of AF recurrence after CA. Incorporating LAAV into pre-ablation screening may enhance risk stratification, guiding tailored follow-up and treatment strategies. PROSPERO REGISTRATION NUMBER: CRD42022339910.

Indexed as

Atrial AppendageAtrial FibrillationCatheter AblationHumansRecurrenceAdult cardiologyMeta-AnalysisPacing & electrophysiology

Identifiers

PMID40623755
PMCPMC12230969

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.