Evidence map›Paper›PMID 40623752›Full record

ArticleBMJ open2025

Developing an evidence brief for policy on implementing deprescribing practices across different levels of healthcare: a protocol.

Mariana Del Grossi Moura, Luis Phillipe Nagem Lopes, Jardel Corrêa de Oliveira, Lais Neiva, Izabela Fulone, Lauren Giustti Mazzei, Danielle Maria de Souza Serio Dos Santos, Luciane Cruz Lopes

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mariana Del Grossi MouraPharmaceutical Sciences Graduate Course, University of Sorocaba, Sorocaba, Brazil.
Luis Phillipe Nagem LopesPharmaceutical Sciences Graduate Course, University of Sorocaba, Sorocaba, Brazil.ORCID http://orcid.org/0000-0002-9186-110X
Jardel Corrêa de OliveiraPharmaceutical Sciences Graduate Course, University of Sorocaba, Sorocaba, Brazil.ORCID http://orcid.org/0000-0002-1178-2787
Lais NeivaPharmaceutical Sciences Graduate Course, University of Sorocaba, Sorocaba, Brazil.
Izabela FulonePharmaceutical Sciences Graduate Course, University of Sorocaba, Sorocaba, Brazil.
Lauren Giustti MazzeiPharmaceutical Sciences Graduate Course, University of Sorocaba, Sorocaba, Brazil.
Danielle Maria de Souza Serio Dos SantosPharmaceutical Sciences Graduate Course, University of Sorocaba, Sorocaba, Brazil.
Luciane Cruz LopesPharmaceutical Sciences Graduate Course, University of Sorocaba, Sorocaba, Brazil luslopesbr@gmail.com.ORCID http://orcid.org/0000-0002-3684-3275

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo identify and contextualise evidence-based strategies for implementing deprescribing practices at different levels of healthcare in Brazil, through the development of an evidence brief for policy that includes stakeholder deliberation and considers barriers, facilitators and equity aspects. METHODS AND ANALYSIS: This protocol outlines the development of an evidence brief for policy using a mixed-methods design. It involves synthesising evidence for health policies by integrating global research and local evidence through three stages: stakeholder exchange, evidence brief development and external endorsement. The Supporting Policy-Relevant Reviews and Trials tools for evidence-informed health policies will guide both the synthesis of strategies and the facilitation of deliberative dialogues. The synthesis will encompass evidence from systematic reviews and meta-analysis on deprescribing strategies across healthcare levels, focusing on effectiveness, harms, costs, perceptions, barriers, facilitators and equity. Studies proposing strategies not yet implemented will be excluded. Study selection and data extraction will be conducted independently and in duplicate. The methodological quality of included studies will be assessed using the A Measurement Tool for Assessing the Methodological Quality of Systematic Reviews-2 criteria. Synthesised evidence will be used to develop evidence-based strategies, which will then be presented in deliberative dialogues for endorsement by stakeholders and adaptation to the Brazilian context. Endorsement rates will be classified as high, moderate or low based on predefined criteria. ETHICS AND DISSEMINATION: This study was approved by the University of Sorocaba Research Ethics Committee (certificate 82098324.7.0000.5500). Informed consent will be obtained from all participants. Findings will be disseminated through peer-reviewed publications and conference presentations. PROSPERO REGISTRATION NUMBER: CRD42024548845.

Indexed as

Delivery of Health CareDeprescriptionsHealth PolicyBrazilHumansResearch DesignSystematic Reviews as TopicDrug UtilizationHealth policyKnowledge

Identifiers

PMID40623752
PMCPMC12230963

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.