Evidence map›Paper›PMID 40623654›Full record

ReviewJournal of lipid research2025

Effects of fasting on HDL particle function and size distribution.

Joanne K Agus, Angela M Zivkovic

Abstract readReview
In one paragraph

Review in Journal of lipid research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joanne K AgusDepartment of Nutrition, University of California, Davis, CA, USA.
Angela M ZivkovicDepartment of Nutrition, University of California, Davis, CA, USA. Electronic address: amzivkovic@ucdavis.edu.

Funding

Comprehensive Characterization of Glycosylation Alterations in Alzheimer’s DiseaseR01AG062240 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JIN, LEE-WAY, LEBRILLA, CARLITO B · 2018 to 2022
$3.3M
Development of a Novel Technology for Preparative Fractionation and Characterization of Lipoprotein ParticlesR01GM147545 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ZIVKOVIC, ANGELA M · 2022 to 2025
$1.2M
NIA NIH HHS R01 AG062240NIGMS NIH HHS R01 GM147545
6 · The paper itself

Abstract

The effects of fasting on high-density lipoprotein (HDL) particles remain an area of ongoing investigation. This narrative review examines the impact of various fasting regimens, including intermittent fasting (IF) and continuous fasting (CF), on HDL cholesterol (HDL-C), particle size distribution, and concentration. Current evidence on fasting's influence on HDL particles is limited and inconsistent, particularly in IF studies, where variability in HDL metrics, recruitment bias, and confounding factors-such as weight loss as a primary study goal-complicate interpretation. While some CF studies suggest a mild trend toward decreased HDL-C and alterations in HDL particle size distribution, the overall health implications of these changes remain unclear. Further research is needed to provide a more comprehensive understanding of how fasting affects HDL particles and their broader implication for health and disease.

Indexed as

Cholesterol, HDLFastingLipoproteins, HDLHumansParticle SizeCholesterol, HDLLipoproteins, HDLhigh density lipoproteinIntermittent fastingparticle concentrationprolonged fastingsize distribution

Identifiers

PMID40623654
PMCPMC12345262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.