Evidence map›Paper›PMID 40623243›Full record

ArticlePain2025

Convergent validity of a person-dependent definition of a low back pain flare.

Pradeep Suri, Anna M Korpak, Andrew K Timmons, Adrienne D Tanus, Hannah F Brubeck, Nathalia Costa, Carina A Staab, Paul W Hodges, Clinton J Daniels, Patrick J Heagerty and 1 more

Abstract read
In one paragraph

Article in Pain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Pradeep SuriRehabilitation Care Services, VA Puget Sound Health Care System, Seattle, WA, United States.ORCID 0000-0002-9449-4165
Anna M KorpakSeattle Epidemiologic Research and Information Center, VA Puget Sound Health Care System, Seattle, WA, United States.
Andrew K TimmonsSeattle Epidemiologic Research and Information Center, VA Puget Sound Health Care System, Seattle, WA, United States.
Adrienne D TanusSeattle Epidemiologic Research and Information Center, VA Puget Sound Health Care System, Seattle, WA, United States.
Hannah F BrubeckSeattle Epidemiologic Research and Information Center, VA Puget Sound Health Care System, Seattle, WA, United States.
Nathalia CostaSchool of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia.
Carina A StaabDepartment of Child, Family, and Population Health Nursing, University of Washington, Seattle, WA, United States.
Paul W HodgesSchool of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia.
Clinton J DanielsRehabilitation Care Services, VA Puget Sound Health Care System, Seattle, WA, United States.
Patrick J HeagertyClinical Learning, Evidence, and Research (CLEAR) Center, University of Washington, Seattle, WA, United States.
Mark P JensenDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA, United States.

Funding

UW Core Center for Clinical Research of Musculoskeletal ConditionsP30AR072572 · NIAMS · UNIVERSITY OF WASHINGTON · PI JEFFREY G JARVIK, Pradeep Suri · 2017 to 2026
$8.3M
Building Research across Interdisciplinary Gaps (BRIDG) T90/R90 Training ProgramT90AT008544 · NCCIH · UNIVERSITY OF WASHINGTON · PI BOOTH-LAFORCE, CATHRYN, BRADLEY, RYAN D · 2015 to 2023
$3.9M
NCCIH NIH HHS T90 AT008544NIAMS NIH HHS P30 AR072572NIAMS NIH HHS P30AR072572Rehabilitation Research and Development Service I01RX003248RRD VA I01 RX003248
6 · The paper itself

Abstract

abstractExacerbations of existing low back pain (LBP) or new LBP episodes are colloquially referred to as "flares." Although the experience of flares is common to many people with LBP, few validated measures enable people to self-report if they are experiencing a flare. This study examined the convergent validity of a person-dependent definition of flares ("a worsening of your low back pain that lasts from hours to weeks") as compared with (1) LBP intensity, (2) LBP-related pain interference, and (3) analgesic use, in a large, prospective research study of Veterans with LBP. Veterans seeking care for LBP (n = 465) were followed prospectively for up to 1 year. Participants completed up to 36 scheduled surveys and additional patient-initiated surveys (triggered by the onset of new flares) over follow-up. Each survey inquired about current flare status, pain intensity measured on a 0 to 10 numeric rating scale (NRS), LBP-related pain interference, and analgesic use. Linear mixed-effects models estimated the association between current flare status and pain intensity, with and without adjustment for potential confounding factors; secondary analyses examined associations with pain interference and analgesic use. In longitudinal analyses of 11,817 surveys, flare status was significantly associated with a 2.8-NRS point greater pain intensity ( P < 0.0001), with and without adjustment for other factors. Statistically significant associations were found between flare status and LBP-related pain interference and analgesic use. New flare periods were associated with impacts on coping, functional limitations, and mood/emotions. These findings support the convergent validity of a person-dependent flare definition.

Indexed as

Low Back PainPain MeasurementAdultAgedAnalgesicsFemaleHumansMaleMiddle AgedProspective StudiesReproducibility of ResultsSelf ReportSurveys and QuestionnairesVeteransAnalgesicsEpidemiologyEpisodesExacerbationsFlare-upsRecurrenceTrajectories

Identifiers

PMID40623243
PMCPMC12252584

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.