Evidence map›Paper›PMID 40623193›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Confinement of ions within graphene oxide membranes enables neuromorphic artificial gustation.

Yuchun Zhang, Lin Liu, Yu Qiao, Tian Yao, Xing Zhao, Yong Yan

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. From Sensing Mechanisms to System Co-Design: Graphene-Based Sensors and Readout Circuits.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuchun Zhang *Chinese Academy of Sciences Key Laboratory of Nanosystem and Hierarchical Fabrication, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China.ORCID 0000-0002-4201-8407
Lin Liu *Chinese Academy of Sciences Key Laboratory of Nanosystem and Hierarchical Fabrication, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China.
Yu Qiao *School of Mathematics and Statistics, Shandong University of Technology, Zibo 255000, China.
Tian YaoChinese Academy of Sciences Key Laboratory of Nanosystem and Hierarchical Fabrication, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China.
Xing ZhaoChinese Academy of Sciences Key Laboratory of Nanosystem and Hierarchical Fabrication, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China.ORCID 0000-0002-9685-3950
Yong YanChinese Academy of Sciences Key Laboratory of Nanosystem and Hierarchical Fabrication, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China.ORCID 0000-0002-5760-7423

Funding

MOST | National Natural Science Foundation of China (NSFC) 22071037MOST | National Natural Science Foundation of China (NSFC) 22201054| Natural Science Foundation of Shandong Province () ZR2022QA065
6 · The paper itself

Abstract

Introducing neuromorphic computing paradigms into taste-sensing technology will bring unprecedented opportunities for developing new hardware architectures with perceptual intelligence. Constructing the biomimetic gustatory system, however, remains a challenge due to the scarcity of suitable components operating under wet conditions. Here, we report that ion confinement within the layered graphene oxide membranes can be used to develop a memristive device capable of implementing both synaptic function and chemical sensing. The continuum model and ion dynamics characterizations demonstrate that interfacial adsorption-desorption slows down ion transport and leads to memristive behavior. Based on this nanofluidic device, we built an artificial gustatory system in the physiological environment, which can efficiently classify different flavors according to the reservoir computing algorithm. Our results suggest a paradigm for in-sensor computing in liquid.

Indexed as

artificial gustatory systemchemical sensinggraphene oxide membraneinterfacial adsorption–desorptionnanofluidic synapse

Identifiers

PMID40623193
PMCPMC12280913

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.