Article in American journal of physiology. Lung cellular and molecular physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors.
Reece P StevensDepartment of Physiology and Cell Biology, Whiddon College of Medicine, University of South Alabama, Mobile, Alabama, United States.ORCID 0000-0001-9209-9527
Jacob HolstonDepartment of Physiology and Cell Biology, Whiddon College of Medicine, University of South Alabama, Mobile, Alabama, United States.ORCID 0009-0005-5564-5441
Karam MaatoukDepartment of Physiology and Cell Biology, Whiddon College of Medicine, University of South Alabama, Mobile, Alabama, United States.
Chun ZhouDepartment of Physiology and Cell Biology, Whiddon College of Medicine, University of South Alabama, Mobile, Alabama, United States.
Madeline StoneDepartment of Physiology and Cell Biology, Whiddon College of Medicine, University of South Alabama, Mobile, Alabama, United States.
Viktoriya V PastukhDepartment of Physiology and Cell Biology, Whiddon College of Medicine, University of South Alabama, Mobile, Alabama, United States.
C Michael FrancisDepartment of Physiology and Cell Biology, Whiddon College of Medicine, University of South Alabama, Mobile, Alabama, United States.ORCID 0000-0001-6001-2618
Sagar KumarPulmonary and Critical Care Division, Department of Internal Medicine, Whiddon College of Medicine, University of South Alabama, Mobile, Alabama, United States.ORCID 0000-0001-5769-1162
Meredith S GwinSection of Pulmonary Critical Care and Sleep Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United States.
Sarah L SaynerDepartment of Physiology and Cell Biology, Whiddon College of Medicine, University of South Alabama, Mobile, Alabama, United States.ORCID 0000-0002-4587-6634
Troy StevensDepartment of Physiology and Cell Biology, Whiddon College of Medicine, University of South Alabama, Mobile, Alabama, United States.ORCID 0000-0001-9689-929X
Ji Young LeeDepartment of Physiology and Cell Biology, Whiddon College of Medicine, University of South Alabama, Mobile, Alabama, United States.ORCID 0000-0002-8005-2446
Funding
T-type Calcium Channels and von Willebrand Factor ReleaseP01HL066299 · NHLBI · UNIVERSITY OF SOUTH ALABAMA · PI STEVENS, TROY · 2001 to 2022
$34.6M
Training Translational Lung Biology and PathobiologyT32HL007778 · NHLBI · YALE UNIVERSITY · PI Erica L Herzog, NAFTALI KAMINSKI · 1994 to 2026
$14.4M
Store-operated calcium entry: lung endothelial permeabilityR37HL060024 · NHLBI · UNIVERSITY OF SOUTH ALABAMA · PI STEVENS, TROY · 2010 to 2019
$3.9M
Store Operated Calcium Entry: Lung Endothelial PermeabilityR01HL060024 · NHLBI · UNIVERSITY OF SOUTH ALABAMA · PI STEVENS, TROY · 1998 to 2009
$3.0M
Acidosis in pulmonary endothelial injury and repairR01HL160988 · NHLBI · UNIVERSITY OF SOUTH ALABAMA · PI Ji Young Lee · 2022 to 2026
$1.9M
Soluble adenylyl cyclases in lung endothelial tauopathyR01HL167997 · NHLBI · UNIVERSITY OF SOUTH ALABAMA · PI Troy Stevens · 2023 to 2026
$1.9M
Lung Endothelial Aß in infectious proteinopathyR01HL148069 · NHLBI · UNIVERSITY OF SOUTH ALABAMA · PI STEVENS, TROY · 2020 to 2023
$1.5M
Carbonic anhydrase IX and pulmonary endothelial cell acidosis during infectionK08HL153958 · NHLBI · UNIVERSITY OF SOUTH ALABAMA · PI LEE, JI YOUNG · 2021 to 2021
$160k
American Heart Association (AHA) 23PRE1020594HHS | National Institutes of Health (NIH) F31NL165873HHS | National Institutes of Health (NIH) HL148069HHS | National Institutes of Health (NIH) HL153958HHS | National Institutes of Health (NIH) HL160988HHS | National Institutes of Health (NIH) HL60024HHS | National Institutes of Health (NIH) HL66299NHLBI NIH HHS K08 HL153958NHLBI NIH HHS P01 HL066299NHLBI NIH HHS R01 HL060024NHLBI NIH HHS R01 HL148069NHLBI NIH HHS R01 HL160988NHLBI NIH HHS R01 HL167997NHLBI NIH HHS R37 HL060024NHLBI NIH HHS T32 HL007778
6 · The paper itself
Abstract
Carbonic anhydrase IX (CA IX) is a unique transmembrane CA isoform that is associated with chronic pulmonary vascular diseases and is upregulated in the lungs during infection. Whether CA IX contributes to alveolar-capillary dysfunction in the acute respiratory distress syndrome (ARDS) is unknown. Here, we tested the hypothesis that CA IX promotes acute lung injury during metabolic acidosis and pneumonia. Wild-type (WT) and CA IX knockout (KO) mice were fed 0.5% sucrose water (control) or 0.28 M NH
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Carbonic anhydrase IX promotes acute lung injury and mortality in females during metabolic acidosis and pneumonia. · full record | OpenQuestion