Evidence map›Paper›PMID 40622842›Full record

ArticlePlant biotechnology journal2025

Co-domestication of cold tolerance and female flower is determined by CsEIN2 in cucumber.

Caixia Li, Shaoyun Dong, Xiaoping Liu, Jiantao Guan, Diane M Beckles, Xingfang Gu, Jiaqiang Sun, Han Miao, Shengping Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Genome-Wide Identification of R2R3-MYB Gene Family in Strawberry (International journal of molecular sciences · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Caixia Li *State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.ORCID https://orcid.org/0000-0002-6365-412X
Shaoyun Dong *State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.ORCID https://orcid.org/0000-0002-8035-8656
Xiaoping Liu *State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Jiantao Guan *State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Diane M BecklesDepartment of Plant Sciences, University of California, One Shield Avenue, Davis, California, USA.
Xingfang GuState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Jiaqiang SunState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.ORCID https://orcid.org/0000-0002-3448-6956
Han MiaoState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Shengping ZhangState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.

Funding

State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, Chinathe Agricultural Science and Technology Innovation Program of the Chinese Academy of Agricultural Sciences (CAAS-ASTIP-2021-IVF)the Basic Research Center, Innovation Program of Chinese Academy of Agricultural Sciences (CAAS-BRC-HS-2025-01)the Earmarked Fund for Modern Agro-industry Technology Research System (CARS-23)the Key Laboratory of Biology and Genetic Improvement of Horticultural Crops, Ministry of Agriculture, P.R. China.the National Key Research and Development Program of China (2023YFD1201503)the National Natural Science Foundation of China (No.32372704;No.31902028)
6 · The paper itself

Abstract

Survive and successful reproduction at cold stress are critical for cucumber adaptation to environmental conditions in high-latitude regions. However, the molecular basis for the co-domestication of cold adaptation and reproductive success in cucumber remains unknown. Here, we demonstrate that CsEIN2 acts as an indispensable hub in regulating both cold tolerance and female flower percentage (FFP) in cucumber. Specifically, we discover that three completely linked natural variations at the C-terminus of CsEIN2, that is, the CsEIN2

Indexed as

Cucumis sativusFlowersPlant ProteinsCold-Shock ResponseCold TemperatureGene Expression Regulation, PlantHaplotypesTranscription FactorsPlant ProteinsTranscription Factorsco‐domesticationcold adaptationCsEIN2cucumberfemale flower developmentnatural allelic variation

Identifiers

PMID40622842
PMCPMC12483969

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.