Evidence map›Paper›PMID 40622760›Full record

ArticleRheumatology (Oxford, England)2025

Frequency, diagnosis, and management of polymyalgia rheumatica in Germany-database analysis of medical insurance data.

Wolfgang A Schmidt, Marco Alibone, Paul Ludwig, Dominik Obermüller, Franziska Karl, Stephanie Terner, Nils Venhoff

Abstract read
In one paragraph

Article in Rheumatology (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wolfgang A SchmidtRheumatology, Waldfriede Hospital, Berlin, Germany.ORCID 0000-0001-7831-8738
Marco AliboneInGef-Institute for Applied Health Research Berlin GmbH, Berlin, Germany.ORCID 0000-0001-8368-7298
Paul LudwigInGef-Institute for Applied Health Research Berlin GmbH, Berlin, Germany.
Dominik ObermüllerInGef-Institute for Applied Health Research Berlin GmbH, Berlin, Germany.
Franziska KarlNovartis Pharma GmbH, Nürnberg, Germany.
Stephanie TernerNovartis Pharma GmbH, Nürnberg, Germany.
Nils VenhoffInternal Medicine, Department of Rheumatology and Clinical Immunology, Medical Center-University of Freiburg, Freiburg, Germany.ORCID 0000-0001-7729-2759

Funding

Novartis GmbH
6 · The paper itself

Abstract

objectivesEpidemiological data on polymyalgia rheumatica (PMR) in Germany is limited. Current national prevalence estimates are low by international standards. This study aimed to gain up-to-date data representative of Germany.

methodsA cross-sectional analysis was conducted on a sample of 4.8 million insured individuals, representative of the German population, from the InGef (Institute for Health Research Berlin GmbH) research database. Inclusion criteria were age ≥50 years, continuous insurance status for a base period of 3 years and for the subsequent 2 years for longitudinal analysis. Results were additionally extrapolated to the German population.

resultsEach year from 2018 to 2021, around 1.7 million insured individuals were included in the study. Extrapolated to the German population in 2021, the incidence was 111/100 000 and the prevalence was 937/100 000. Diagnosis was made predominantly in outpatient settings (86.7%) most frequently by general practitioners (GP; 37.1%), internists (22.2%), rheumatologists (11.4%) and orthopaedists (10.2%). An additional 21% were referred to rheumatologists for treatment after diagnosis. Treatment was most commonly initiated by GPs, followed by rheumatologists, and included methotrexate in 19.8%. Most common comorbidities of prevalent patients comprised arterial hypertension (75.9%), dyslipidaemia (55.0%), diabetes mellitus (29.7%), osteoporosis (27.1%), coronary heart disease (23.4%) and cataract (24.3%).

conclusionThis analysis revealed that PMR occurs more frequently in individuals aged 50 or older in Germany than previously assumed. Diagnosis is primarily made in general practice settings, with about one-third of patients being treated by rheumatologists. Comorbidities such as diabetes mellitus or cardiovascular diseases are common in the prevalent population.

Indexed as

Polymyalgia RheumaticaAgedAged, 80 and overAntirheumatic AgentsCross-Sectional StudiesDatabases, FactualFemaleGermanyHumansIncidenceInsurance, HealthMaleMethotrexateMiddle AgedPrevalenceAntirheumatic AgentsMethotrexatecomorbiditiesglucocorticoidsincidencemedical insurance datamethotrexatepolymyalgia rheumaticaprevalence

Identifiers

PMID40622760
PMCPMC12598749

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.