Evidence map›Paper›PMID 40622674›Full record

ArticleSpine deformity2025

All-pedicle screw posterior spinal fusion after magnetically controlled growing rods in walking early-onset scoliosis patients: radiographic and surgical outcomes.

Sergio De Salvatore, Paolo Brigato, Leonardo Oggiano, Davide Palombi, Gian Mario Sangiovanni, Edoardo Costici, Sergio Sessa, Pier Francesco Costici

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Article in Spine deformity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Sergio De Salvatore *Orthopedic Unit, Department of Surgery, Bambino Gesù Children's Hospital, Rome, Italy. sergio.desalvatore@gmail.com.
Paolo Brigato *Research Unit of Orthopaedic and Trauma Surgery, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo, 00128, Rome, Italy.
Leonardo OggianoOrthopedic Unit, Department of Surgery, Bambino Gesù Children's Hospital, Rome, Italy.
Davide PalombiDepartment of Pediatric Neurosurgery, Fondazione Policlinico Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168, Rome, Italy.
Gian Mario SangiovanniDepartment of Statistical Sciences, Sapienza University of Rome, Rome, Italy.
Edoardo CosticiFaculty of Medicine and Surgery, Saint Camillus International, University of Health Sciences, 00131, Rome, Italy.
Sergio SessaOrthopedic Unit, Department of Surgery, Bambino Gesù Children's Hospital, Rome, Italy.
Pier Francesco CosticiOrthopedic Unit, Department of Surgery, Bambino Gesù Children's Hospital, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEarly-onset scoliosis (EOS) significantly affects lung development and life expectancy. Magnetically Controlled Growing Rods (MCGR) effectively promote thoracic growth while managing curvature progression. This study aims to assess the impact of definitive spinal fusion on residual deformity and complications in EOS patients treated with MCGRs.

methodsThe study included 27 EOS patients who underwent final fusion surgery between January 2017 and September 2022. The primary outcome was the evaluation of coronal and sagittal radiographic parameters postoperatively and at a minimum of 2 years of follow-up (FUP). Secondary outcomes included major complications (≥ IIIB, according to Clavien-Dindo Classification), surgery duration, blood loss and length of hospital stay (LOS).

resultsMajor curve (45.5° and 33.5°, p = 0.003, Brunner-Munzel Test Statistic = - 3.869254) and Thoracic Kyphosis (TK) (19.8° and 13.5°, p = 0.002, Brunner-Munzel Test Statistic = - 2.258845) were statistically impacted by arthrodesis, and maintained at the final follow-up. The surgeries had an average duration of 254.2 ± 39.5 min (range: 195-336 min) and an average blood loss of 574.1 ± 255.1 mL (range: 200-1300 mL). The mean LOS was 8.5 ± 1.8 days (range: 6-13 days). Following the final fusion, 5 patients (18.5%) developed a complication, of which one was classified as major.

conclusionsThis study demonstrated substantial improvements in coronal and sagittal alignment following graduation surgery, with results maintained at the two-year FUP. Further research with larger sample sizes is needed to provide a more comprehensive assessment of radiographic and surgical outcomes and to establish guidelines for implant density in MCGR graduation surgery.

Indexed as

Pedicle ScrewsScoliosisSpinal FusionChildFemaleFollow-Up StudiesHumansKyphosisLength of StayMalePostoperative ComplicationsRadiographyRetrospective StudiesThoracic VertebraeTreatment OutcomeWalkingEarly onset scoliosisEOSMAGECMagnetically controlled growing rodMCGRPosterior spinal fusionSurgical outcomes

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.