Evidence map›Paper›PMID 40622583›Full record

ArticleBiological cybernetics2025

Basal ganglia: an amplifier for preparatory activity in motor control.

Serhat Çağdaş, Neslihan Serap Şengör

Abstract read
PubMed Publisher
In one paragraph

Article in Biological cybernetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Serhat ÇağdaşElectrical-Electronics Engineering Department, Yalova University, Çınarcık Yolu, Yalova, 77200, Türkiye. serhat.cagdas@yalova.edu.tr.
Neslihan Serap ŞengörElectronics and Communication Engineering Department, Istanbul Technical University, Maslak, Istanbul, 34469, Türkiye.

Funding

ITU Scientific Research Projects Office MDK-2022-43588
6 · The paper itself

Abstract

The basal ganglia make a significant contribution to the generation of motor behavior through their involvement in the descending motor pathways. Gaining insight into how the motor cortex produces motor patterns is also a key to understanding the function of the basal ganglia. The population dynamics approach is convenient for the reevaluation of the behavior of the motor cortex and also the roles of other components in the motor system. Here, it is proposed that the basal ganglia amplify preparatory activity in the motor cortex with the modulatory effect of phasic dopamine release. The influence of the basal ganglia is tested with a computational model on a center-out-reaching task. The results show that the basal ganglia facilitate movement initiation and increase the robustness of the behavior. These results, based on the perspective of population dynamics, may improve our understanding of the role of the basal ganglia in motor control and the symptoms of dopamine-related conditions in neurodegenerative diseases of motor control.

Indexed as

Basal GangliaModels, NeurologicalMotor ActivityMotor CortexAnimalsComputer SimulationDopamineHumansMovementDopamineAmplifierBasal gangliaMotor controlPopulation dynamics

Identifiers

PMID40622583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.