ReviewAdvances in experimental medicine and biology2025
Innate Immune Response to Helminth Infections.
Review in Advances in experimental medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Editorial: Helminthosis: immuno-pathology and anthelmintic vaccines.Frontiers in immunology · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Helminths are the most common infectious parasites of humans, causing a global burden of disease, exceeding malaria and tuberculosis in developing countries. Helminth parasites have coevolved with humans and thus are quite well adapted to survive and flourish in them. The immune response induced by the parasite is predominantly pro-inflammatory, a Th1-mediated response involving antigen-presenting cells with elevated IgE and eosinophilia. At the later stage, the parasite is capable of polarizing the Th1 response to the Th2 response, which becomes favorable for their survival for a longer period inside the host, leading to chronic infection. This chapter elaborates the intricate and complex life cycle of different helminthic parasites, the various antigenic components expressed and shed off by the parasite inside human host, the innate immune response mediate by the host against the parasite, and the survival strategies undertaken by the parasite to dampen the surveillance mechanism against them.
Indexed as
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40622546What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.