ReviewAdvances in experimental medicine and biology2025
Collectins and Ficolins.
Review in Advances in experimental medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protein-carbohydrate interactions are utilized by the immune system for several defense activities. Collectins and ficolins have a key role in maintaining the balance of surfactants in the lungs and supporting the immune system in the lungs, respectively. This chapter provides an extensive description of two soluble pattern recognition receptors (PRRs), collectins and ficolins. It covers their structure, specificity for binding to certain ligands, biological functions along with initiating immune response by various mechanisms, their genetic characteristics, associations with various diseases, and their potential for use in therapy and diagnosis. The potential of collectins as diagnostic markers and therapeutic agents in diverse malignancies for their antitumorigenic effects has also been investigated. These findings have greatly enhanced our understanding of the innate immune system's previously overlooked specificity and effectiveness.
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40622542What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.