ArticleSurgery today2025
Impact of low anterior resection syndrome after rectal surgery on sleep quality.
Article in Surgery today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Living with low anterior resection syndrome after rectal cancer surgery: challenges, self-management, and supportive care priorities.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Development and validation of web-based prediction models for major low anterior resection syndrome at 3 and 6 months after sphincter-preserving surgery in patients with rectal cancer.International journal of colorectal disease · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe factors contributing to the association between rectal cancer and sleep impairment remain unclear. We investigated the risk factors for sleep impairment after anus-preserving surgery for rectal cancer.
methodsThis cross-sectional study investigated surviving patients who underwent low anterior or intersphincteric resection with curative intent for rectal cancer located < 15 cm from the anal verge. Defecatory dysfunction and sleep quality were assessed using the low anterior resection syndrome (LARS) score and the Pittsburgh Sleep Quality Index, respectively.
resultsA total of 176 patients were included in this analysis. The sleep impairment rate in the "major LARS" group was significantly higher than that in the "no/minor LARS" group (54.5 vs. 24.2%; p < 0.001). Multivariable analysis identified that age (odds ratio = 0.943) and tumor height (odds ratio = 0.893) were independently associated with major LARS. In the multivariable analysis for sleep impairment, major LARS (odds ratio = 4.490, p < 0.001) and adjuvant (pre/post) chemotherapy (odds ratio = 3.400, p = 0.003) were independently associated with sleep impairment.
conclusionSleep quality was reduced significantly in patients with major LARS after rectal cancer surgery. Adjuvant chemotherapy also impairs sleep quality, while low tumor location and young age were independent risk factors for major LARS.
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