Evidence map›Paper›PMID 40622380›Full record

ArticleJournal of the International AIDS Society2025

Scale of differentiated service delivery implementation in HIV care facilities in low- and middle-income countries: a global facility survey.

Nathalie Verónica Fernández Villalobos, Fabrice Helfenstein, Vohith Khol, Christella Twizere, Mayara Secco, Barbara Castelnuovo, Jacqueline Huwa, Thierry Tiendredbeogo, C William Wester, Siew Moy Fong and 19 more

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Article in Journal of the International AIDS Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Nathalie Verónica Fernández VillalobosInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0001-7560-5256
Fabrice HelfensteinInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Vohith KholNational Center for HIV/AIDS, Dermatology & STDs, Phnom Penh, Cambodia.
Christella TwizereCentre National de Référence en matière de VIH/SIDA (CNR), Bujumbura, Burundi.ORCID https://orcid.org/0000-0003-1102-5564
Mayara SeccoInstituto Nacional de Infectologia Evandro Chagas (INI), Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Barbara CastelnuovoInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Jacqueline HuwaLighthouse Trust, Lilongwe, Malawi.
Thierry TiendredbeogoUniversity of Bordeaux, National Institute for Health and Medical Research (INSERM) UMR 1219, Research Institute for Sustainable Development (IRD) EMR 271, Bordeaux Population Health Research Centre, Bordeaux, France.ORCID https://orcid.org/0000-0002-9393-9732
C William WesterDivision of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center (VUMC), Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0002-8375-3926
Siew Moy FongDepartment of Pediatrics, Hospital Likas, Kota Kinabalu, Malaysia.
Gad MurenziEinstein-Rwanda Research and Capacity Building Program, Research for Development and Rwanda Military Referral and Teaching Hospital, Kigali, Rwanda.ORCID https://orcid.org/0000-0002-5513-5522
Yanink Caro-VegaDepartamento de Infectología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.ORCID https://orcid.org/0000-0001-9212-1560
Rita Elias LyamuyaMorogoro Regional Hospital - CTC, Indiana University, Morogoro, Tanzania.
Idiovinio RafaelSolidarMed, Pemba, Mozambique.
Djimon Marcel ZannouCentre national de référence pour la recherche et la prise en charge des PVVIH au Centre National Hospitalier Universitaire HK MAGA (CNHU-HKM), Cotonou, Bénin.
Kathy PetoumenosThe Kirby Institute, UNSW Sydney, Sydney, New South Wales, Australia.
Dominique Mahambou NsondeCentre de Traitement Ambulatoire of Brazzaville, Brazzaville, Congo.
Jorge PintoUniversidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Kara Wools-KaloustianDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Carolyn Bolton MooreCentre for Infectious Disease Research in Zambia (CIDRZ), Lusaka, Zambia.ORCID https://orcid.org/0000-0001-9103-7746
Ounoo Elom TakassiLome University, Lome, Togo.
Sasisopin KiertiburanakulFaculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0003-4379-4704
Rogers Ajeh AwohUniversity of Buea, Buea, Cameroon.ORCID https://orcid.org/0000-0002-5361-5063
Shamim M AliSchool of Medicine, College of Health Sciences, Moi University, Eldoret, Kenya.
Geoffrey FattiKheth'Impilo AIDS Free Living, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-6467-662X
Karen MalatesteUniversity of Bordeaux, National Institute for Health and Medical Research (INSERM) UMR 1219, Research Institute for Sustainable Development (IRD) EMR 271, Bordeaux Population Health Research Centre, Bordeaux, France.
Elizabeth ZaniewskiInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Marie BallifInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
International epidemiology Databases to Evaluate AIDS

Funding

North American AIDS Cohorts on Collaboration and Design (NAACCORD)U01AI069918 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Keri Nicole Althoff, RICHARD Douglas MOORE · 2006 to 2026
$65.2M
East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional ConsortiumU01AI069911 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Leslie Anne Enane, AGGREY SEMWENDERO SEMEERE · 2006 to 2026
$57.7M
Observational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9M
The Asia-Pacific HIV Research CollaborationU01AI069907 · NIAID · FOUNDATION FOR AIDS RESEARCH · PI ANNETTE H SOHN · 2006 to 2026
$44.8M
CCASAnet: Caribbean, Central and South America NetworkU01AI069923 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Pedro Enrique Cahn, Jessica L Castilho · 2006 to 2026
$41.6M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8M
WADA (West Africa Database on Antiretroviral Therapy) CollaborationU01AI069919 · NIAID · UNIVERSITY OF BORDEAUX II · PI Didier Koumavi Ekouevi, Antoine Jaquet · 2006 to 2026
$29.9M
Harmonist: A Scalable Toolkit for Standardizing and Coordinating Data Sharing Across International Research NetworksR24AI124872 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Stephany Norah Duda · 2016 to 2026
$12.5M
Malawi HIV Implementation Research Scientist Training Program (MHIRST)D43TW010060 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MINA CHRISTINE HOSSEINIPOUR, Victor Mwapasa · 2015 to 2026
$3.8M
FIC NIH HHS D43 TW010060FIC NIH HHS U01AI069907FIC NIH HHS U01AI069911FIC NIH HHS U01AI069918FIC NIH HHS U01AI069919FIC NIH HHS U01AI069923FIC NIH HHS U01AI069924FIC NIH HHS U01AI096299Informatics resources are supported by the Harmonist project R24AI24872National Institute of Allergy and Infectious Diseases R24AI24872NCATS NIH HHS UL1 TR000445NIAID NIH HHS R24 AI124872NIAID NIH HHS U01 AI069907NIAID NIH HHS U01 AI069911NIAID NIH HHS U01 AI069918NIAID NIH HHS U01 AI069919NIAID NIH HHS U01 AI069923NIAID NIH HHS U01 AI069924NIAID NIH HHS U01 AI096299Research Electronic Data Capture TR000445
6 · The paper itself

Abstract

introductionIn 2016, the World Health Organization recommended differentiated service delivery (DSD) as a client-centred approach to simplify HIV care in frequency and intensity, thus reducing the clinic visit burden on individuals and HIV programmes. We describe the scale of DSD implementation among HIV facilities in low- and middle-income countries (LMICs) in Latin America, Africa and the Asia-Pacific before the COVID-19 pandemic.

methodsWe analysed facility-level survey data from HIV care facilities participating in the International epidemiology Databases to Evaluate AIDS consortium in 2019. We used descriptive statistics to summarise the availability of DSD, multi-month dispensing (MMD) and DSD for HIV treatment models. We explored factors associated with DSD implementation using multivariable models.

resultsWe included 175 facilities in the Asia-Pacific (n = 30), Latin America (n = 8), Central Africa (n = 21), East Africa (n = 74), Southern Africa (n = 28) and West Africa (n = 14). Overall, 133 facilities (76%) reported implementing DSD. Of these, 91% offered DSD for HIV treatment, 61% for HIV testing and 59% for antiretroviral therapy (ART) initiation. The most common duration of ART refills for clinically stable clients was 3MMD, (70%), followed by monthly (14%) and 6MMD (10%). Facility-based individual models were the most frequently available DSD for the HIV treatment model (82%), followed by client-managed group models (60%). Out-of-facility individual models were available at 48% of facilities. Facility-based individual models were particularly common among facilities in East (92%) and Southern Africa (96%). Facilities in medium and high HIV prevalence countries, and those with 3MMD, were more likely to implement DSD.

conclusionsIn 2019, DSD was available in most HIV care facilities globally but was not evenly implemented across regions and HIV services. Most offered facility-based DSD for HIV treatment models and 3MMD for clinically stable clients. Efforts to expand DSD for HIV testing and ART initiation and to offer longer MMD can improve long-term retention in care of people living with HIV in LMICs, while further alleviating the operational burden on healthcare services. These findings from the pre-COVID-19 era underline the need for strengthening DSD in HIV care, which remains at the centre of current efforts towards client-centred care.

Indexed as

Delivery of Health CareHealth FacilitiesHIV InfectionsCOVID-19Developing CountriesHumansLatin Americaantiretroviral therapydifferentiated service deliveryHIVkey and vulnerable populationslow‐ and middle‐income countriespatient‐centred care

Identifiers

PMID40622380
PMCPMC12232477

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.