Evidence map›Paper›PMID 40622246›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2025

Plaque-Targeted Delivery of Fluoride-Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy.

Qianqian Bai, Xinyue Lao, Sin-Yi Pang, Yifei Zhao, Yuan Liu, Xiao Yu Tian, Jianhua Hao

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qianqian BaiDepartment of Applied Physics, The Hong Kong Polytechnic University, Hong Kong, 999077, P. R. China.ORCID https://orcid.org/0000-0002-6698-3324
Xinyue LaoDepartment of Applied Physics, The Hong Kong Polytechnic University, Hong Kong, 999077, P. R. China.
Sin-Yi PangDepartment of Applied Physics, The Hong Kong Polytechnic University, Hong Kong, 999077, P. R. China.ORCID https://orcid.org/0000-0003-1023-5316
Yifei ZhaoDepartment of Applied Physics, The Hong Kong Polytechnic University, Hong Kong, 999077, P. R. China.
Yuan LiuDepartment of Applied Physics, The Hong Kong Polytechnic University, Hong Kong, 999077, P. R. China.
Xiao Yu TianSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, 999077, P. R. China.
Jianhua HaoDepartment of Applied Physics, The Hong Kong Polytechnic University, Hong Kong, 999077, P. R. China.ORCID https://orcid.org/0000-0002-6186-5169

Funding

Hong Kong Polytechnic University 1-W30M,1-CE0H,1-CD7V,1-YWC0,1-CE0MPolyU GrantsResearch Grants Council of the Hong Kong Special Administration Region GRFNo.15303123,PolyUSRFS2122-5S02,HKPDFSRef.PDFS2324-5S09
6 · The paper itself

Abstract

Atherosclerosis is an oxidative stress-induced chronic inflammatory condition underpinning the progression of cardiovascular diseases (CVDs), ultimately resulting in leading mortality rate globally. Ultrasound (US)-triggered catalysis offers localized treatment for deep-seated plaques effectively and safely, with demand for targeted delivery and anti-inflammatory properties of sonosensitizers. 2D MXene-based nanomedicine is garnering attention because of their intriguing catalytic properties of scavenging excessive reactive oxygen species (ROS), yet MXene-assisted sonocatalytic therapy (SCT) for treating CVDs remains scarce. Here, this study reports a dual enzyme-mimicking and US-responsive MXene termed Nb

Indexed as

AtherosclerosisPlaque, AtheroscleroticAnimalsCatalysisHumansMaleMiceMice, Inbred C57BLNitritesPolyethylene GlycolsRAW 264.7 CellsReactive Oxygen SpeciesTransition ElementsUltrasonic WavesMXeneNitritesPolyethylene GlycolsReactive Oxygen SpeciesTransition Elements2D materialscardiovascular diseasesfluoride‐free MXenenanomedicinesonocatalytic therapy

Identifiers

PMID40622246
PMCPMC12676089

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.