Evidence map›Paper›PMID 40622216›Full record

ArticleMicrobiology spectrum2025

Exogenous adenosine counteracts tigecycline resistance in

Jing Sun, Yiming Liu, Jiashen Chang, Ying Liu, Luqi Li, Ran Jiang, Yihan Luo, Shuo Yang, Mei Yang, Xinglong Wang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jing Sun *College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Yiming LiuCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Jiashen ChangCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Ying LiuCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Luqi LiLife Science Research Core Services, Northwest A&F University, Yangling, Shaanxi, China.
Ran JiangCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Yihan LuoCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Shuo YangCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Mei YangCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Xinglong WangCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.ORCID 0000-0002-5764-8209
Juan WangCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Xi XiaNational Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China.ORCID 0000-0002-9630-7909
Kangkang GuoCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Zengqi YangCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Dongyang Ye *College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.ORCID 0000-0003-2564-1608

Funding

China Postdoctoral Science Foundation 2023M732888National Natural Science Foundation of China 32302928
6 · The paper itself

Abstract

The rapid spread of antibiotic resistance poses a global health crisis. Tigecycline is a last-resort antibiotic, but the recent emergence of the plasmid-borne

Indexed as

AdenosineAnti-Bacterial AgentsDrug Resistance, BacterialEscherichia coliTigecyclineAnimalsEscherichia coli InfectionsEscherichia coli ProteinsMetabolomicsMicrobial Sensitivity TestsAdenosineAnti-Bacterial AgentsEscherichia coli ProteinsTigecyclineadenosineantimicrobial resistancemetabolomicstet(X3)tigecycline

Identifiers

PMID40622216
PMCPMC12323663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.