Observational studyThe Journal of dermatology2025
NEVIGRAV Study: A Case-Control Analysis on Changes in Melanocytic Nevi During Pregnancy.
Observational study in The Journal of dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Pregnancy-Associated Melanoma: A Molecular Reappraisal of the Hormonal Hypothesis, Illustrated by a Postpartum-Persistent Melanoma In Situ.Diagnostics (Basel, Switzerland) · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pregnancy can influence modifications and appearance of melanocytic nevi, but studies report inconsistent findings, often lacking standardized methods and comparison groups. This study evaluates dermoscopic changes in nevi and the development of new melanocytic lesions in pregnant women using full-body photography and digital dermoscopy. Nevigrav is an observational case-control study conducted at two university dermatology centers, involving 85 participants (45 pregnant women and 40 controls) with 1614 lesions analyzed. Participants were asked about recent sun exposure or tanning habits. Enrollment was predominantly conducted in autumn and winter months to minimize ultraviolet (UV) exposure as a confounding factor. Total body photography revealed no new lesions in pregnant women when compared to controls. Dimensional growth was observed in the abdomen (p = 0.049) and the back (p < 0.001) between the first and second trimesters, with further abdominal growth in the third trimester (p < 0.001). At the third trimester, pigmentation changes were significant, with phototype III maintaining or increasing pigmentation and phototype II showing a reduction of pigmentation (χ
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Registered trials
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