Evidence map›Paper›PMID 40622073›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2025

Mitochondrial Calcium Uniporter-Mediated Regulation of the SIRT3/GSK3β/β-Catenin Signaling Pathway in Vascular Remodeling.

Min Jiang, Lejian Lin, Shuai Yue, Shujin Shi, Haojie Yan, Hui Yi, Fan Han, Shuai Xu, Junjie Su, Ran Zhang

Abstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Journal of thoracic disease · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Mitochondrial Calcium Uniporter-Mediated Regulation of the SIRT3/GSK3β/β-Catenin Signaling Pathway in Vascular Remodeling.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Min JiangDepartment of Pulmonary and Critical Care Medicine, Chinese PLA General Hospital, Beijing, China.
Lejian LinDepartment of Cardiovascular Medicine, Chinese PLA General Hospital, Beijing, China.
Shuai YueDepartment of Cardiovascular Medicine, Chinese PLA General Hospital, Beijing, China.
Shujin ShiDepartment of Cardiovascular Medicine, Chinese PLA General Hospital, Beijing, China.
Haojie YanDepartment of Cardiovascular Medicine, Chinese PLA General Hospital, Beijing, China.
Hui YiDepartment of Cardiovascular Medicine, Chinese PLA General Hospital, Beijing, China.
Fan HanDepartment of Cardiovascular Medicine, Chinese PLA General Hospital, Beijing, China.
Shuai XuDepartment of Cardiovascular Medicine, Chinese PLA General Hospital, Beijing, China.
Junjie SuDepartment of Cardiovascular Medicine, Chinese PLA General Hospital, Beijing, China.
Ran ZhangDepartment of Cardiovascular Medicine, Chinese PLA General Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-0921-078X

Funding

Medical Science and Technology Youth Cultivation Program 21QNPY133MOST | National Natural Science Foundation of China (NSFC) 82171857MOST | National Natural Science Foundation of China (NSFC) 82302114
6 · The paper itself

Abstract

Calcium homeostasis plays a crucial role in regulating the phenotype of vascular smooth muscle cells (VSMCs) and vascular remodeling. This study aims to investigate the role of the mitochondrial calcium uniporter (MCU), which facilitates the uptake of Ca

Indexed as

beta CateninCalcium ChannelsGlycogen Synthase Kinase 3 betaSirtuin 3Vascular RemodelingAngiotensin IIAnimalsCalciumMaleMitochondriaMuscle, Smooth, VascularMyocytes, Smooth MuscleOxidative StressRatsRats, Sprague-DawleySignal TransductionAngiotensin IIbeta CateninCalciumCalcium ChannelsCtnnb1 protein, ratGlycogen Synthase Kinase 3 betaGsk3b protein, ratmitochondrial calcium uniporterSIRT3 protein, ratSirtuin 3Sirtuinsangiotensin IIcalciumGSK3β/β‐cateninhindlimb unloadingmicrogravitymitochondrial calcium uniporterSIRT3vascular remodeling

Identifiers

PMID40622073
PMCPMC12232586

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.