Evidence map›Paper›PMID 40622017›Full record

ReviewKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2025

The metaverse in orthopaedics: Virtual, augmented and mixed reality for advancing surgical training, arthroscopy, arthroplasty and rehabilitation.

Mahmut Enes Kayaalp, Efstathios Konstantinou, Bedri Karaismailoglu, Gian Andrea Lucidi, Mehmet Kaymakoglu, Romed Vieider, Joseph D Giusto, Jumpei Inoue, Michael T Hirschmann

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07515092 naenrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Virtual Reality-Based Simulation Training for Antegrade Anterior Column Acetabular Screw Placement in Orthopedic Residents: A Crossover Randomized Controlled Trial

TypeinterventionalSponsorBangkok Metropolitan Administration Medical College and Vajira HospitalRan2026 to 2027Enrolled20ConditionsVirtual Reality SimulationArmsVirtual reality based simulation training, Standard Training
NCT07636278 recruitingnot on this mapstarted 2026, after this paper: background citation

Artificial Intelligence-Based Identification of the Target Zone on Arthroscopic Images During Knee Anterior Cruciate Ligament Reconstruction: An Observational Study

TypeobservationalSponsorI.R.C.C.S Ospedale Galeazzi-Sant'AmbrogioRan2026 to 2027Enrolled100ConditionsAnterior Cruciate Ligament (ACL) TearArmsPrimary arthroscopic anterior cruciate ligament reconstruction
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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  2. [Virtual reality and digital shoulder surgery].Orthopadie (Heidelberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mahmut Enes KayaalpDepartment of Orthopaedics and Traumatology, Istanbul Fatih Sultan Mehmet Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye.ORCID https://orcid.org/0000-0002-9545-7454
Efstathios KonstantinouDepartment of Orthopaedic Surgery and Musculoskeletal Trauma, University Hospital of Larisa, School of Health Sciences, University of Thessaly, Larisa, Greece.ORCID https://orcid.org/0000-0002-8379-8593
Bedri KaraismailogluCAST (Cerrahpasa Research, Simulation and Design Laboratory), Istanbul University-Cerrahpasa, Istanbul, Türkiye.
Gian Andrea LucidiII Clinica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Mehmet KaymakogluDepartment of Orthopedics and Traumatology, Faculty of Medicine, Izmir University of Economics, Izmir, Türkiye.ORCID https://orcid.org/0000-0002-3548-5672
Romed VieiderDepartment of Orthopaedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Joseph D GiustoDepartment of Orthopaedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Jumpei InoueDepartment of Orthopaedic Surgery, Nagoya Tokushukai General Hospital, Kasugai, Aichi, Japan.
Michael T HirschmannDepartment of Orthopedic Surgery and Traumatology, Kantonsspital Baselland, Bruderholz, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe metaverse and extended reality (XR), which includes augmented reality (AR), virtual reality (VR) and mixed reality (MR), are transforming orthopaedic surgery by enhancing training, procedural accuracy and rehabilitation. However, a literature review of these new virtual tools is lacking. The purpose of this narrative review is to summarise available evidence about the metaverse and discuss current and future clinical applications.

methodsA narrative review of the current literature was performed for studies evaluating XR tools and their respective clinical and educational utility. Studies from all orthopaedic subspecialties were eligible for inclusion. The XR tools evaluated in each study were categorised according to the reality spectrum and future research or clinical applications were discussed.

resultsXR is a technological spectrum that includes AR, VR and MR to create immersive and interactive surgical training environments. VR-based simulators may improve surgical education by allowing trainees to refine their skills in a risk-free setting. AR may enhance intraoperative guidance and has been studied within orthopaedics to improve implant positioning accuracy and reduce complications in procedures including arthroscopy and total joint arthroplasty. In rehabilitation, AR and VR have been implemented to facilitate patient engagement and adherence, promoting functional recovery through gamified therapy and remote telerehabilitation.

conclusionsThere has been a paradigm shift in orthopaedic care in which digital tools are integrated with patient care to optimise patient outcomes. However, challenges to the widespread implementation of promising XR technology include high costs, steep learning curves and limited clinical validation. Ethical concerns, including data security and patient privacy, further complicate its use in clinical settings. Future research must focus on cost-effectiveness, standardisation and improving accessibility to ensure seamless integration into clinical practice. LEVEL OF EVIDENCE: Level V.

Indexed as

ArthroscopyAugmented RealityOrthopedic ProceduresOrthopedicsVirtual RealityClinical CompetenceHumansSimulation Trainingaugmented realityeducation, medical, graduateorthopedic proceduresrehabilitationvirtual reality

Identifiers

PMID40622017
PMCPMC12310088

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.