Evidence map›Paper›PMID 40621947›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2025

Functional alignment in robotic total knee arthroplasty achieves comparable outcomes in varus and valgus knees despite distinct intraoperative strategies: Analysis of 355 consecutive cases.

Christos Koutserimpas, Clemente Caria, Pietro Gregori, Luca Andriollo, Elvire Servien, Cécile Batailler, Sébastien Lustig

Abstract readComparative Study
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  4. Functional alignment: Defined personalized alignment strategy with promising outcomes and room for improvement.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christos KoutserimpasSchool of Rehabilitation Health Sciences, University of Patras, Patras, Greece.ORCID https://orcid.org/0000-0002-1398-9626
Clemente CariaOrthopaedics Surgery and Sports Medicine Department, FIFA Medical Center of Excellence, Croix-Rousse Hospital, Lyon University Hospital, Lyon, France.
Pietro GregoriOrthopaedics Surgery and Sports Medicine Department, FIFA Medical Center of Excellence, Croix-Rousse Hospital, Lyon University Hospital, Lyon, France.
Luca AndriolloOrthopaedics Surgery and Sports Medicine Department, FIFA Medical Center of Excellence, Croix-Rousse Hospital, Lyon University Hospital, Lyon, France.
Elvire ServienOrthopaedics Surgery and Sports Medicine Department, FIFA Medical Center of Excellence, Croix-Rousse Hospital, Lyon University Hospital, Lyon, France.
Cécile BataillerOrthopaedics Surgery and Sports Medicine Department, FIFA Medical Center of Excellence, Croix-Rousse Hospital, Lyon University Hospital, Lyon, France.
Sébastien LustigOrthopaedics Surgery and Sports Medicine Department, FIFA Medical Center of Excellence, Croix-Rousse Hospital, Lyon University Hospital, Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFunctional alignment (FA) optimises implant positioning based on patient-specific anatomy, but data on intraoperative adjustments in varus and valgus knees remain limited. This study evaluates the impact of preoperative coronal alignment on implant positioning, bone resections, functional outcomes, and revision rates in robotic-assisted total knee arthroplasty (TKA) under FA principles.

methodsA retrospective analysis of 355 robotic-assisted TKAs performed with FA was conducted. Patients were classified as varus (n = 294, HKA < 180°) or valgus (n = 61, HKA ≥ 180°). Intraoperative implant positioning, bone resections, and alignment parameters were recorded. Functional outcomes were assessed using the Knee Society Scores, Forgotten Joint Score, and Kujala score. Implant survivorship was analysed using the Kaplan-Meier method.

resultsVarus knees required greater tibial varus positioning (3.5° varus [interquartile range [IQR] 2-5] vs. 1° varus [IQR 0-2.5], p < 0.0001), while valgus knees required increased femoral valgus positioning (1.5° [IQR 0.38-2.5] vs. 0.7° [IQR -0.5 to 1.83], p = 0.0004). Bone resections also differed significantly between groups. Specifically, the valgus group had lower lateral tibial (p = 0.0001), distal lateral (p < 0.0001), and posterior lateral femoral resections (p < 0.0001), but higher distal medial femoral resections (p = 0.04). Postoperative functional outcomes were comparable across groups. Survival rates were 98.64% (varus) and 98.36% (valgus) (p = 0.86), with a hazard ratio of 1.23 (95% CI: 0.12-12.57) for valgus knees.

conclusionThis study systematically evaluates intraoperative modifications in FA-based robotic TKA for varus and valgus knees. Despite distinct balancing strategies, both groups achieved comparable outcomes and implant survivorship. LEVEL OF EVIDENCE: Level III.

Indexed as

Arthroplasty, Replacement, KneeBone MalalignmentKnee JointOsteoarthritis, KneeRobotic Surgical ProceduresAgedFemaleFemurHumansKnee ProsthesisMaleMiddle AgedReoperationRetrospective StudiesTreatment Outcomecoronal alignmentfunctional alignmentfunctional knee positioningrobotic knee

Identifiers

PMID40621947
PMCPMC12582244

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.