Evidence map›Paper›PMID 40621929›Full record

ArticleMicrobiology spectrum2025

Molecular determinants of substrate specificity in the efflux pump CraA from

Wuen Ee Foong, Xinxin Xiang, Klaas M Pos, Heng-Keat Tam

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wuen Ee FoongDepartment of Biochemistry and Molecular Biology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.ORCID 0000-0003-2402-7729
Xinxin XiangDepartment of Biochemistry and Molecular Biology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Klaas M PosInstitute of Biochemistry, Goethe-University Frankfurt, Frankfurt am Main, Germany.ORCID 0000-0001-9035-3827
Heng-Keat TamDepartment of Biochemistry and Molecular Biology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.ORCID 0000-0002-7894-1957

Funding

Deutsche Forschungsgemeinschaft DFG Research Unit FOR 2251HSTD | Natural Science Foundation of Hunan Province () 2024JJ5326Science and Technology Innovation Program of Hunan Province 2024RC9011University of South China 221RGC012
6 · The paper itself

Abstract

The major facilitator superfamily (MFS) type efflux pumps of

Indexed as

Acinetobacter baumanniiBacterial ProteinsMembrane Transport ProteinsAnti-Bacterial AgentsBiological TransportDrug Resistance, Multiple, BacterialEscherichia coliEscherichia coli ProteinsSubstrate SpecificityAnti-Bacterial AgentsBacterial ProteinsEscherichia coli ProteinsMdfa protein, E coliMembrane Transport ProteinsAcinetobacter baumanniiefflux pumpsmajor facilitator superfamilymultidrug resistancesubstrate polyspecificity

Identifiers

PMID40621929
PMCPMC12323617

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.