Evidence map›Paper›PMID 40621864›Full record

ArticleExperimental physiology2025

Intermittent hand and forearm immersion in 20°C water attenuates thermal, cardiovascular, and perceptual strain in older adults during heat stress.

Rachel M Cottle, Kat G Fisher, Olivia K Leach, David E Conroy, Lacy M Alexander, W Larry Kenney

Abstract read
In one paragraph

Article in Experimental physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rachel M CottleDepartment of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-6567-9785
Kat G FisherDepartment of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0009-0002-5231-1719
Olivia K LeachDepartment of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0009-0004-6934-7755
David E ConroyDepartment of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0000-0003-0204-4093
Lacy M AlexanderDepartment of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-1294-8582
W Larry KenneyDepartment of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-1326-8175

Funding

Psychosocial Determinants and Biological Pathway to Healthy Aging (Pathways)T32AG049676 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI LYNN M. MARTIRE · 2016 to 2026
$3.9M
Identification of Critical Thermal Environments for Aged AdultsR01AG067471 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI KENNEY, W. LARRY · 2020 to 2024
$3.7M
NIA NIH HHS R01 AG067471NIA NIH HHS T32 AG049676NIH HHS R01 AG067471
6 · The paper itself

Abstract

Adults >65 years of age experience deleterious health effects during extreme heat events at a greater rate than any other age cohort. The purpose of this study was to identify the effectiveness of acute intermittent hand and forearm (H+F) water immersion and/or chronic (7 week) folic acid supplementation on reducing thermal and cardiovascular strain in older adults during heat stress. Twelve older adults (six female; 65-89 years of age) were exposed to 2 h of heat stress at 34°C and 77% relative humidity during seated rest, with and without H+F immersion, following folic acid or placebo supplementation. During immersion trials, participants immersed both H+F in cool tap water (∼20°C) for 10 min at min 60 and 90. Core temperature, skin temperature and heart rate were monitored continuously, and blood pressure and the rate-pressure product were recorded every 10 min. Data were analysed as absolute changes and as a delta from min 50 (i.e., immediately before cooling). There was no effect of folic acid on any variable (all p > 0.05). Absolute and delta core temperature, skin temperature and heart rate increased over time (p ≤ 0.041); however, H+F water immersion attenuated this increase (p ≤ 0.046) after the first cooling bout. Likewise, absolute and delta RPP increased over time (p ≤ 0.047), but absolute RPP was attenuated with H+F water immersion (p = 0.003). These data suggest that intermittent H+F water immersion effectively attenuates thermal and cardiovascular strain for older adults at rest during heat stress.

Indexed as

ageingcooling strategiesheat wavesrate–pressure productthermal stress

Identifiers

PMID40621864
PMCPMC13394156

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.