Evidence map›Paper›PMID 40621818›Full record

Trial reportAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Creating harmony at home via environmental cueing: A feasibility trial of a non-pharmacological intervention for rural caregivers of persons with dementia.

Elizabeth K Rhodus, Richard Kryscio, Gregory Jicha, Carolyn Baum, Laura Henley, Vickie Fairchild, Celeste Roberts, Allison Gibson

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05202223 (Creating Harmony at HOME), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05202223 nacompletednot on this map

Creating Harmony at HOME: A Pilot Study of a Telehealth Based Program for Rural Caregivers' Ability to Adapt Home Environments for Adults With ADRD

TypeinterventionalSponsorElizabeth K RhodusRan2022 to 2022Enrolled80ConditionsAlzheimer Disease, Dementia, Brain Diseases, Central Nervous System DiseasesArmsHarmony at HOME (H@H)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elizabeth K RhodusSanders-Brown Center on Aging, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.ORCID 0000-0001-5108-0766
Richard KryscioSanders-Brown Center on Aging, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Gregory JichaSanders-Brown Center on Aging, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Carolyn BaumProgram in Occupational Therapy, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
Laura HenleySanders-Brown Center on Aging, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Vickie FairchildSt. Claire Healthcare, Morehead, Kentucky, USA.
Celeste RobertsSanders-Brown Center on Aging, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Allison GibsonSaint Louis University, School of Social Work, St. Louis, Missouri, USA.

Funding

University of Kentucky Alzheimer's Disease Research CenterP30AG072946 · NIA · UNIVERSITY OF KENTUCKY · PI Daniel Carl Lee · 2021 to 2026
$23.5M
University of Kentucky Alzheimer's Disease Core Center - Biomarker CoreP30AG028383 · NIA · UNIVERSITY OF KENTUCKY · PI GOLD, BRIAN TIMOTHY, VAN ELDIK, LINDA J · 2006 to 2020
$23.3M
Roybal Translational Research Center to Promote Context-Specific Caregiving of Community-Dwelling Persons Living with Alzheimer's Disease or Related DisordersP30AG064200 · NIA · EMORY UNIVERSITY · PI Ken W Hepburn, Molly M Perkins · 2019 to 2026
$8.6M
Improving Person-Environment Fit of Community-Residing Older Adults with Dementia Through Assessment and Individualized InterventionK23AG075262 · NIA · UNIVERSITY OF KENTUCKY · PI Elizabeth Rhodus · 2022 to 2026
$895k
Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (NIA/AA IMPACT-AD) CourseU13AG067696 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GRILL, JOSHUA, RAMAN, REMA · 2020 to 2024
$375k
NIA NIH HHS K23 AG075262NIA NIH HHS L30 AG079409NIA NIH HHS P30 AG028383NIA NIH HHS P30 AG064200NIA NIH HHS P30 AG072946NIA NIH HHS U13 AG067696NIH/NIA K23AG075262NIH/NIA P30AG028383NIH/NIA P30AG064200
6 · The paper itself

Abstract

introductionBehavioral and psychiatric symptoms of dementia (BPSDs) and functional impairment have a major impact on quality of life for people living with dementia (PLWD). Development of caregiver-initiated interventions, including environmental assessment and modification, are priorities in the field.

methodsAn open-label study of 40 caregivers of PLWD with BPSDs that underwent a 6-week telehealth person-environment intervention, Harmony at HOME, was conducted. Feasibility was assessed by improved caregiver mastery.

resultsTwenty-eight caregivers completed the intervention, which increased caregiver mastery and decreased stress and burden. There were statistically significant improvements in functional performance of the person living with dementia (p < 0.005) and caregivers' satisfaction with the person living with dementia's functional performance (p < 0.001). DISCUSSION: The intervention increased caregivers' skills and knowledge in assessing and modifying the environment to address BPSDs. Although overall caregiver mastery was not changed significantly, additional clinical research assessing caregiver mastery in relation to specific caregiving tasks within the home environment is needed. CLINICAL

trial registrationClinicaltrials.gov NCT05202223 HIGHLIGHTS: Aging in place is difficult to achieve for individuals with dementia. A novel dyadic care intervention, Harmony at HOME, improved caregiver outcomes. Future care research should explore performance-based patient outcomes.

Indexed as

CaregiversCuesDementiaAgedAged, 80 and overFeasibility StudiesFemaleHumansMaleMiddle AgedQuality of LifeRural PopulationTelemedicinebehavioral and psychiatric symptoms of dementiacaregiver masteryenvironmental cueingnon‐pharmacological interventionoccupational therapyperson–environment fittelehealth

Identifiers

PMID40621818
PMCPMC12230769

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.