ArticleContact dermatitis2025
Sensitization Patterns to Cyanoacrylate-Based Surgical Glues.
Article in Contact dermatitis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Systemic Allergic Dermatitis to Cyanoacrylate Used for Embolisation.Contact dermatitis · 2025Article
- Sensitization Patterns to Cyanoacrylate-Based Surgical Glues.Contact dermatitis · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurgical glues are increasingly used, offering advantages like reduced scarring and faster wound closure. However, they pose risks of localised and disseminated allergic contact dermatitis caused by cyanoacrylate monomers.
objectivesThis study aims to evaluate sensitisation patterns to cyanoacrylate-based surgical glues, the usefulness of testing with the commercially available ethyl cyanoacrylate, and cross-reactions between cyanoacrylates and (meth)acrylates. PATIENTS/
methodsSixteen patients with suspected allergic contact dermatitis (ACD) from surgical adhesives were patch tested with the European Standard and Acrylate series (only containing ethyl cyanoacrylate) among other series, of whom 15 were tested with the surgical glues used. Clinical data, including demographics and surgical histories, were collected.
resultsFifteen patients (94%) tested positively to surgical glues, with 81% showing positive reactions to ethyl cyanoacrylate, to which the patient not tested to the glue "as is" also reacted. Three ethyl cyanoacrylate-negative patients reacted to Dermabond Prineo. Exclusive sensitisation to ethyl cyanoacrylate was observed in eight patients, while five reacted to other (meth)acrylic compounds.
conclusionsEthyl cyanoacrylate is a screening agent for surgical-glue sensitised patients, but if negative, tape-stripping-modified patch testing, also with the glues, is indicated. Cross-reactions can occur between cyanoacrylates and co-reactions (concomitant sensitization) with certain (meth)acrylates. Primary sensitisation is particularly relevant in patients undergoing treatment with cyanoacrylate-based glues for the first time, rather than because of previous exposure to other sources.
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