Trial reportBrain and behavior2025
Effects of Auditory Frequency Stimulation on Balance and Rehabilitation Outcomes in Patients With Stroke: A Randomized Case-Control Study.
Trial report in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The Effects of 40 Hz Gamma Binaural Beat Auditory Stimulation on Postural Control, Motor Coordination, and Cognitive Function Among Healthy Adults: A Pilot Study.Journal of clinical medicine · 2026Article
- Recent research on rehabilitation interventions for post-stroke gait and balance in low- and middle-income countries: a scoping review.BMC health services research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundAlthough the role of sensory input in maintaining balance is well established, the effects of various auditory frequency stimulations, such as binaural beat stimulation (BBS), on patients with central nervous system injuries, particularly those who have experienced a stroke, remain inadequately understood.
methodsThis randomized case-control study compared the functional outcomes between patients with stroke undergoing BBS during rehabilitation training and those receiving traditional music therapies. The assessed primary outcomes included balance function, balance confidence, lower-limb function, and activities of daily living, cognitive abilities, and depression scores. Subsequently, correlations between outcome parameters were analyzed.
resultsA total of 27 patients with stroke completed the study protocol (BBS n = 15, control n = 12). Post-intervention analyses revealed improvements in balance-related indicators, particularly the scores of the Berg Balance Scale (BBSc) and Mini-Balance Evaluation Systems Test (Mini-BESTest), across both groups. However, the Barthel index (BI) and Beck depression inventory scores (BDIS) in the BBS group exhibited significantly greater improvements than those in the control group. Correlation analyses indicated that changes in balance-related scores within the BBS group were associated with improvements in lower-limb function, mood, and activities of daily living. Conversely, the control group observed correlations among the internal components of the balance-related scales.
conclusionAppropriate BBS stimulation appears to enhance balance, likely owing to the synergistic effects of music and rhythm. Further research focusing on brain function is necessary to elucidate the mechanisms underlying the therapeutic efficacy of BBS interventions.
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