ReviewPakistan journal of medical sciences2025
Effect of human immunodeficiency virus self-testing (HIVST) on HIV and STI testing uptake among men who have sex with men (MSM): A systematic review and meta-analysis of randomized controlled trials.
Review in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Genetic polymorphism of CCR5 (59029A/G) and CCR2 (-64I A/G) promoters in HIV infected patients.Pakistan journal of medical sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Objectives: The objective of this review was to assess the effectiveness of HIVST in terms of increasing HIV testing, early detection of HIV, and sexually transmitted infections among MSM via HIVST. Methods: We conducted a systematic review and meta-analysis of randomized controlled trials. We searched PubMed/MEDLINE, EMBASE, Cochrane Central, and clinicaltrials.gov. Data were extracted from May 2013- May 2024. RCTs comparing HIVST with traditional HIV testing among MSM were included in the review. Data was analyzed using Review Manager version five. Results: A total of fifteen randomized controlled trials (RCTs) were identified and included in the qualitative synthesis, and thirteen were included in the meta-analysis. The mean difference in HIV test results between the HIVST group and the traditional HIV testing group was 2.07 (95% confidence interval (CI) 1.54--2.60). The odds ratio for the detection of incident HIV in the HIVST group was 1.55 (95% confidence interval 1.02-2.37). The odds ratio of HIV test uptake from eleven RCTs was 5.17 (95% confidence interval 1.90-14.06) for HIVST compared with traditional HIV testing. Pooled analysis revealed that the odd ratio of STI test uptake was 0.86 among the HIVST group compared with the traditional HIV testing group (P <.02). Conclusions: HIVST is associated with increased uptake of HIV testing and an increased mean number of HIV tests among MSM. It also leads to increased detection of HIV. However, STI testing decreases with HIVST, likely because of facility-based HIV testing in the control arm.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.