Evidence map›Paper›PMID 40621459›Full record

ArticleFrontiers in immunology2025

Sex-based immunological differences in multisystem inflammatory syndrome in children: potential role of T

Flavia Carriero, Monica Gelzo, Valentina Rubino, Giulia Scalia, Alice Castaldo, Vincenzo Tipo, Antonietta Giannattasio, Carolina D'Anna, Giuseppina Ruggiero, Giuseppe Castaldo and 1 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Flavia Carriero *Department of Health Sciences, University of Basilicata, Potenza, Italy.
Monica Gelzo *Centro di Ingegneria Genetica e Biotecnologie Avanzate F. Salvatore (CEINGE) Advanced Biotechnology Franco Salvatore, Naples, Italy.
Valentina RubinoDepartment of Translational Medical Sciences, University of Naples Federico II, Naples, Italy.
Giulia ScaliaCentro di Ingegneria Genetica e Biotecnologie Avanzate F. Salvatore (CEINGE) Advanced Biotechnology Franco Salvatore, Naples, Italy.
Alice CastaldoAzienda Ospedaliera di Rilievo Nazionale (AORN) Santobono-Pausilipon Hospital, Naples, Italy.
Vincenzo TipoAzienda Ospedaliera di Rilievo Nazionale (AORN) Santobono-Pausilipon Hospital, Naples, Italy.
Antonietta GiannattasioAzienda Ospedaliera di Rilievo Nazionale (AORN) Santobono-Pausilipon Hospital, Naples, Italy.
Carolina D'AnnaAzienda Ospedaliera di Rilievo Nazionale (AORN) Santobono-Pausilipon Hospital, Naples, Italy.
Giuseppina Ruggiero *Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy.
Giuseppe Castaldo *Centro di Ingegneria Genetica e Biotecnologie Avanzate F. Salvatore (CEINGE) Advanced Biotechnology Franco Salvatore, Naples, Italy.
Giuseppe Terrazzano *Department of Health Sciences, University of Basilicata, Potenza, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multisystem Inflammatory Syndrome in Children (MIS-C) is characterized by immune dysregulation, exhibiting clinical and immunological features reminiscent of autoimmune processes, although its underlying mechanisms remain incompletely understood. This study examines immune system alterations in MIS-C patients, focusing on T

Indexed as

COVID-19Systemic Inflammatory Response SyndromeT-Lymphocytes, RegulatoryAdolescentBiomarkersChildChild, PreschoolFemaleHumansInfantLymphocyte ActivationMaleSARS-CoV-2Sex CharacteristicsSex FactorsBiomarkersbiomarkersimmune regulationMIS-Csex-based differencesTR3-56 cellsTreg

Identifiers

PMID40621459
PMCPMC12226297

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.