ReviewRSC advances2025
Review on various activator-assisted polymer grafting techniques for smart drug delivery applications.
Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Modification of Chitosan with (-)-Gossypol and (-)-Gossypol Acetic Acid Using Free-Radical Grafting Method.International journal of molecular sciences · 2025Article
- From Conventional to Next-Generation Strategies: Recent Advances in Polymeric Micelle Preparation for Drug Delivery.Pharmaceutics · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Activator-assisted polymer grafting has emerged as a crucial approach in the development of advanced drug delivery systems, enabling precise regulation of drug release, targeting, and biocompatibility. In contrast to traditional formulation techniques, activator-mediated grafting methods, including redox initiation, photo-induced reactions, plasma treatment, and enzymatic catalysis, provide improved functionalization of polymers, achieving high grafting efficiency and adjustable properties. This review presents a thorough assessment of polymer grafting methodologies, encompassing grafting-to, grafting-from, and grafting-through techniques, with a detailed examination of the function of activators in facilitating these processes. The focus is directed towards enhancing polymer solubility, mucoadhesion, and responsiveness to physiological stimuli through these strategies, ultimately leading to optimized therapeutic performance. Furthermore, the review examines current developments and biomedical applications of activator-assisted grafted polymers, particularly in targeted drug delivery, tissue engineering, and formulations tailored for specific diseases. The insights presented aim to guide the development of advanced polymers that demonstrate superior efficacy, minimize systemic toxicity, and enhance patient adherence.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.