Evidence map›Paper›PMID 40621335›Full record

ArticleCureus2025

Association Between Erectile Dysfunction and Lower Urinary Tract Symptoms in a North Indian Tertiary Care Hospital.

Rishikant Gyani, Apul Goel, Satyanarayan Sankhwar, Bhupendra P Singh, Manoj Kumar, Vivek Kumar Singh

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rishikant GyaniUrology, King George's Medical University, Lucknow, IND.
Apul GoelUrology, King George's Medical University, Lucknow, IND.
Satyanarayan SankhwarUrology, Institute of Medical Sciences, Varanasi, IND.
Bhupendra P SinghUrology, King George's Medical University, Lucknow, IND.
Manoj KumarUrology, King George's Medical University, Lucknow, IND.
Vivek Kumar SinghUrology, King George's Medical University, Lucknow, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction This study aimed to investigate the relationship between erectile dysfunction (ED) and lower urinary tract symptoms (LUTS) in a North Indian population, as well as to assess the influence of age, serum prostate-specific antigen (PSA), and testosterone levels on this association. Materials and methods A cross-sectional study was conducted at King George's Medical University, Lucknow, India, involving 183 men aged ≥50 years presenting with LUTS or benign prostatic hyperplasia (BPH). The severity of ED was assessed using the International Index of Erectile Function-15 (IIEF-15), while LUTS severity was measured using the International Prostate Symptom Score (IPSS). Serum PSA and testosterone levels were evaluated. Statistical analysis was performed using IBM SPSS Statistics for Windows, Version 26.0 (Released 2018; IBM Corp., Armonk, NY, United States), with a significance level set at p < 0.05. Results The patients' mean ± SD age was 63.13 ± 8.98 years. The severity of LUTS was classified as mild in 67 patients (36.6%), moderate in 62 (33.8%), and severe in 54 (29.5%). ED was categorized as mild in 92 patients (50.3%), moderate in 73 (39.9%), and severe in 18 (9.8%). A significant correlation was found between ED severity and increasing age (p < 0.001), as well as with higher IPSS (p < 0.05). Additionally, ED was significantly associated with comorbidities, including hypertension (HTN) and diabetes mellitus (DM) (p < 0.05). Furthermore, IIEF-15 scores showed a significant correlation with testosterone levels (r = 0.679, p < 0.001). No significant correlation was found between ED severity and serum PSA levels. Conclusions This study found a significant association between ED and the severity of LUTS in men with BPH. The data revealed that patients over 79 years of age tended to have lower testosterone levels, and the presence of comorbidities such as HTN and DM emerged as major risk factors for ED. These findings highlight the significance of adopting a comprehensive, multifactorial approach to assess and manage ED in patients with LUTS.

Indexed as

benign prostatic hyperplasiaerectile dysfunctioninternational index of erectile functioninternational prostate symptom scorelower urinary tract symptoms

Identifiers

PMID40621335
PMCPMC12227428

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.