ArticleCureus2025
Anemia in Patients With Pituitary Adenomas: Prevalence and Correlation With Hypopituitarism.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Fatigue in acromegaly patients: a scoping review.Frontiers in endocrinology · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionReports on the prevalence of anemia in pituitary tumors are rare. This study aimed to establish the prevalence of anemia at the time of diagnosis in a cohort of patients with acromegaly, non-secretory pituitary adenomas (NFA), and prolactinomas. A secondary objective was to evaluate the coexistence of hypopituitarism and anemia. MATERIALS AND
methods
resultsAnemia was diagnosed in 68 (19.8%) patients: 22 (32.35%) with acromegaly (average hemoglobin (aHb): 11.8 g/dL), 29 (42.65%) with NFA (aHb: 11.6) and 17 (25%) with prolactinomas (aHb: 11.5). The prevalence was significantly higher in men, with 45 cases (27%), compared to 23 (13%) cases in women (p = 0.002). Most cases had mild anemia, 65 (96.6%). Regarding the classification according to mean corpuscular volume and mean corpuscular hemoglobin concentration values, 59 (87%) had normocytic normochromic anemia. Testosterone and thyroxine deficiency did not significantly affect the frequency of anemia. Anemia was associated with hypocortisolism (p= 0.027) and growth hormone deficiency (IGF-1) in the NFA group (p= 0.009).
conclusionThis study shows a high prevalence of anemia, particularly in men, among patients with pituitary adenomas. The results improve knowledge of the comorbidities in patients with pituitary adenomas and suggest the importance of monitoring blood counts in patients' evolution, given the impact of anemia on general health.
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