Evidence map›Paper›PMID 40621306›Full record

ArticleCureus2025

Spinal Epidural Abscess: Raising the Index of Suspicion.

Daniel Prabahkar, Iqra Qazi, Sunita Devi, Samar Eldahtoury, Aamer W Janjua

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel PrabahkarDepartment of Medicine, Sam Houston State University College of Osteopathic Medicine, Conroe, USA.
Iqra QaziDepartment of Medicine, Baptist Hospitals of Southeast Texas, Beaumont, USA.
Sunita DeviDepartment of Medicine, Baptist Hospitals of Southeast Texas, Beaumont, USA.
Samar EldahtouryDepartment of Medicine, Baptist Hospitals of Southeast Texas, Beaumont, USA.
Aamer W JanjuaDepartment of Medicine, Sam Houston State University College of Osteopathic Medicine, Conroe, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A spinal epidural abscess is an uncommon but life-threatening infection. Typically, it arises secondary to an insult that provides bacterial entry into the bloodstream. Often, spinal epidural abscesses are managed with a combination of surgical intervention and systemic antibiotics in order to minimize the risk of antibiotic resistance and recurrence. The standard of diagnosis for spinal epidural abscesses is through contrast-enhanced magnetic resonance imaging (MRI), which has high sensitivity and specificity. This particular case describes an indolent course of a spinal epidural abscess that presented with neurological deficits unaccounted for by preliminary spinal imaging, underscoring the value of clinical reasoning in patient assessment. An 81-year-old Caucasian female was brought to the emergency department by her daughter with concern of low back pain and a 12-hour history of weakness in the bilateral lower extremities. Her lumbar pain worsened with spinal extension and improved with spinal flexion. She denied any injury, fever, or bowel and bladder incontinence. A review of her past surgical history revealed a recent left shoulder arthroplasty complicated by postoperative cellulitis. She denied any alcohol, tobacco, or drug use. At presentation, her respiratory rate was 28 breaths/minute, and all other vital signs were within normal limits. A physical exam demonstrated bilateral lower extremity strength 3/5, straight leg raising test positive on the right, and the remainder of the exam was unremarkable. To investigate mechanical spinal cord compression, an MRI without contrast of the lumbar spine was obtained. This revealed chronic degenerative changes and failed to explain her acute onset of weakness. Complete blood count revealed a white blood cell count of 16.0 x10

Indexed as

atypical symptomsdelayed diagnosismethicillin-sensitive staphylococcus aureus (mssa)peripheral neuropathyspinal epidural abscessspinal infections

Identifiers

PMID40621306
PMCPMC12229139

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.