Evidence map›Paper›PMID 40621238›Full record

ArticleCureus2025

Pancreatic Plasmacytoma Presenting as Acute Pancreatitis: An Unusual Extramedullary Onset of Multiple Myeloma.

Bakr Alhayek, Xiaowei Malone, Ariba Khan, Raja Gummalla, Ryan Brink

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bakr AlhayekInternal Medicine, AdventHealth Tampa, Tampa, USA.
Xiaowei MaloneInternal Medicine, AdventHealth Tampa, Tampa, USA.
Ariba KhanInternal Medicine, AdventHealth Tampa, Tampa, USA.
Raja GummallaInternal Medicine, AdventHealth Tampa, Tampa, USA.
Ryan BrinkInternal Medicine, AdventHealth Tampa, Tampa, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) typically manifests with bone pain, anemia, and hypercalcemia. Extramedullary disease (EMD), particularly pancreatic involvement, is rare. We report a 63-year-old woman presenting with acute pancreatitis secondary to a pancreatic plasmacytoma. Initial symptoms included epigastric pain, elevated lipase (1,389 U/L), and imaging revealing a 12.1 cm pancreatic mass. Biopsy confirmed lambda-restricted plasma cells (CD138+). Bone marrow biopsy showed 15% clonal plasma cells, meeting the diagnostic criteria for MM. EMD in MM signifies aggressive disease and poor prognosis.

Indexed as

acute pancreatitisextramedullary diseasemultiple myelomapancreatic masspancreatic plasmacytoma

Identifiers

PMID40621238
PMCPMC12228989

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.