ArticleCureus2025
A Case of Spontaneous Tumor Lysis Syndrome With Acute Kidney Injury and the Timing of Chemotherapy.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Tumor lysis syndrome (TLS) is an oncological emergency that can lead to acute kidney injury (AKI), cardiac arrhythmias, seizures, and death. TLS typically arises after initiation of chemotherapy. However, spontaneous TLS (STLS) can occur rarely. Here, we present the case of a 56-year-old male with HIV-associated stage IV diffuse large B-cell lymphoma, who presents with STLS with severe AKI. With hemodialysis, febuxostat, and dose-adjusted chemotherapy, successful resolution of metabolic derangements and return of his baseline kidney function was achieved. Our case aims to provide insight into when to initiate chemotherapy in STLS patients with severe AKI.
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