Evidence map›Paper›PMID 40621232›Full record

ArticleCureus2025

Congenital Absence of the Left Atrial Appendage and Possible Effects on Thrombosis: A Case Report.

Harthik Kambhampati, Shivang Patel, Matthew Thomas, Jalal Ibrahim, Ambar Patel

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Harthik KambhampatiMedicine, Lake Erie College of Osteopathic Medicine, Bradenton, USA.
Shivang PatelMedicine, Lake Erie College of Osteopathic Medicine, Bradenton, USA.
Matthew ThomasPediatrics and Child Health, Lake Erie College of Osteopathic Medicine, Bradenton, USA.
Jalal IbrahimMedicine, Lake Erie College of Osteopathic Medicine, Bradenton, USA.
Ambar PatelCardiology, St. Vincent's Medical Center, Jacksonville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The left atrial appendage (LAA) is a common site for thrombus formation in atrial fibrillation (AF) and often the focus of imaging prior to cardioversion. We present a rare case of a 64-year-old male undergoing routine transesophageal echocardiography (TEE) prior to electrical cardioversion, during which the LAA was not visualized. Further evaluation confirmed congenital absence of the LAA - a seldom-reported finding with uncertain implications for stroke risk and anticoagulation management. This report adds to the limited literature on this anomaly and underscores the importance of a systematic approach when faced with unexpected imaging findings. Although the absence of the LAA might theoretically reduce thromboembolic risk, current evidence is insufficient to alter management, and standard anticoagulation guidelines for AF should still be followed.

Indexed as

cardiologycase reportleft atrial appendage absenceradiologytransthoracic echocardiography

Identifiers

PMID40621232
PMCPMC12228944

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.