Evidence map›Paper›PMID 40621144›Full record

ArticleJournal of clinical and experimental dentistry2025

Evaluation the Effect of Rosmarinic Acid as an Antioxidant Agent on Shear Bond Strength of Resin Composite to Bleached Enamel.

Hamideh Sadat Mohammadipour, Majid Akbari, Moona Zamanpour, Atefeh Nemati-Karimooy, Arsalan Shahri, Mehrzad Khorshid

Abstract read
In one paragraph

Article in Journal of clinical and experimental dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hamideh Sadat MohammadipourAssociate Professor, Dental Materials Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Department of Restorative Dentistry, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
Majid AkbariProfessor, Department of Restorative Dentistry, Dental Research center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
Moona ZamanpourDentist, Mashhad, Iran.
Atefeh Nemati-KarimooyAssistant Professor, Department of Restorative and Cosmetic Dentistry, Dental Research center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
Arsalan ShahriDentist, Research Assistant, Dental Materials Research Center, Mashhad Dental School, Mashhad University of Medical Sciences, Mashhad, Iran.
Mehrzad KhorshidDentist, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Tooth bleaching, a routine esthetic dental procedure, can compromise bond strength to enamel and dentin, especially if composite restorations are bonded immediately post-bleaching due to residual peroxide and free radicals. To address this, various treatments, including antioxidants like sodium ascorbate (SA), have been used, though SA may increase bacterial accumulation. Rosmarinic acid (RA), an alternative antioxidant, offers additional antibacterial and adhesive benefits. This study evaluates the effect of RA application time on shear bond strength (SBS) in bleached enamel, comparing its efficacy with SA under varying treatment durations. Three null hypotheses regarding RA's impact on SBS are tested. Material and Methods: The labial surfaces of 60 freshly extracted bovine incisors were randomly assigned into 6 groups and subjected to a specific surface treatment as follows: no bleaching procedure (NBL), bleaching with 38% hydrogen peroxide (BL), BL+ 10% sodium ascorbate for 10 min (SA), BL+ RA for 10 seconds (RA1), 60 seconds (RA2) and 10 min (RA3). The resin composite was bonded to enamels s immediately after these treatments. After storage in water for 24 hours, the bonded samples were mounted on a universal testing machine and loaded to the fracture point. Data analysis was performed using Kolmogorov-Smirnov, Lilliefors, One-way analysis of variance and Games-Howell tests. Results: The NBL group had the highest SBS, comparable only to SA ( Conclusions: Rosmarinic acid was not able to reverse the bond strength to enamel immediately after the bleaching process, regardless of the duration of application.

Identifiers

PMID40621144
PMCPMC12225771

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