The Academic Research Organization Alliance for Southeast and East Asia (ARISE) in the new era: An international trials network towards pandemic preparedness.

The Academic Research Organizations (ARO) Alliance for Southeast and East Asia (ARISE), established in 2021, is a network of academic research organizations in Southeast and East Asia. Its founding vision was focused on conducting effective, high-quality clinical research and providing timely access to new medicinal products during health crises. Through its focused efforts, ARISE has fostered regional cooperation and contributed to implementing clinical trials of medical products in its network. In response to global health challenges, the Government of Japan is establishing a new organization, the Japan Institute for Health Security, with functions encompassing infectious disease control and pandemic preparedness. As ARISE continues to fulfill its mission of addressing emerging infectious diseases, the ongoing changes in its founding organization will significantly impact its operations. With this article, we aim to highlight ARISEs achievements in its first two years and to explain how its strategy has been adapted to the new organizational structure and evolving global health landscape. ARISE strives to strengthen its network collaboration and further enhance the ability of member organizations to respond rapidly and effectively to future health emergencies.