Evidence map›Paper›PMID 40621079›Full record

ReviewJournal of ginseng research2025

Therapeutic potential of ginsenosides in circadian rhythm-based skin disorders.

Heejun Ha, Heeseon Shin, Sukhyun Min, Natasha Christabella Sutopo, Khamit Yerkesh, Eunsun Jung, Minkyung Song, Jae Youl Cho, Jongsung Lee

Abstract readReview
In one paragraph

Review in Journal of ginseng research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Ginsenosides fromJournal of ginseng research · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Heejun HaMolecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon, Republic of Korea.
Heeseon ShinMolecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon, Republic of Korea.
Sukhyun MinMolecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon, Republic of Korea.
Natasha Christabella SutopoDepartment of Biocosmetics, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon, Republic of Korea.
Khamit YerkeshDepartment of Biocosmetics, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon, Republic of Korea.
Eunsun JungBiospectrum Life Science Institute, Seongnam, Republic of Korea.
Minkyung SongIntegrative Research of T Cells Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Department of Biopharmaceutical Convergence, Sungkyunkwan University, Republic of Korea.
Jae Youl ChoMolecular Immunology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon, Republic of Korea.
Jongsung LeeMolecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The circadian rhythm, a biological system all living organisms possess, has become increasingly important as sleep patterns become more irregular. Circadian rhythms affect various cell types (fibroblasts, fat cells, muscles, etc.) and organs (the liver, pancreas, gut, etc.). This review focuses on the effects of the circadian rhythm on skin physiology. Under normal conditions, the circadian rhythm is involved in maintaining skin health, including DNA repair and wound healing. Disrupted circadian rhythm can cause skin disorders, including hyperpigmentation, melanoma, skin aging, sunburn, impaired wound healing, and an abnormal skin barrier. Furthermore, the effects of ginsenosides, the primary bioactive component of

Indexed as

Circadian rhythmGinsenosidesSkin disordersSkin physiology

Identifiers

PMID40621079
PMCPMC12223530

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.