ReviewClinical, cosmetic and investigational dermatology2025
The Impact of Psychological Stress on Wound Healing: Implications for Neocollagenesis and Scar Treatment Efficacy.
Review in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Refractory Stasis Dermatitis Due to Chronic Venous Insufficiency With Psychosocial Worsening in 2 Septuagenarian Patients Treated With Hyaluronic Acid-Succinic Acid Intradermotherapy.The American journal of case reports · 2026Article
- [Current status of post-traumatic growth among university students and its mediation pathway with post-traumatic stress symptoms].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026Article
- Review
- Enzyme-AssistedInternational journal of molecular sciences · 2026Article
- Review
- Article
- Impact of chronic social stress on molecular markers of skin regeneration during experimental excisional wounding.Frontiers in immunology · 2025Article
- Effects of Perioperative Noise Exposure on Sleep Quality and Psychological Stress in Patients Undergoing Lung Cancer Surgery.Noise & healthObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Psychological stress is a well-established inhibitor of wound healing, yet its specific impact on scar treatment efficacy remains underexplored. Given the significance of collagen synthesis in wound healing and various advanced scar treatments, an investigation into the impact of psychological stress on these processes is warranted. This review examines the biological mechanisms of wound healing and collagen formation, focusing on how psychological stress disrupts these pathways and impacts scar treatment outcomes. Current literature indicates that psychological stress impairs collagen production and reduces the efficacy of scar treatments. These findings underscore the importance of integrating stress management into scar treatment protocols and highlight the need for further research into combined physiological and psychological approaches to optimize healing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.